Canagliflozin Powder CAS 842133-18-0 Raw Materials

CAS: 842133-18-0

MF: C24H25FO5S

Specification​: 99% min Canagliflozin Powder

Sample:  Canagliflozin Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Canagliflozin Powder Usage and Synthesis:

Canagliflozin is an oral medication used to treat type 2 diabetes. It works by blocking the reabsorption of glucose in the kidneys, causing excess glucose to be excreted in the urine. This helps to lower blood sugar levels in people with diabetes. Canagliflozin is often used in combination with other diabetes medications and lifestyle changes, such as diet and exercise. It is sold under the brand name Invokana. Canagliflozin is a prescription medication and should only be taken under the guidance of a healthcare professional.

Canagliflozin is a SGLT2 inhibitor that reduces blood sugar by breaking down glucose and expelling it from the body through the kidneys. In addition to good blood sugar control, Canagliflozin is most notable for its weight loss and few hypoglycemic events. Have broad prospects.

Pharmacokinetics of Canagliflozin Powder:

Cagliflozin is a drug used to treat type 2 diabetes, and its main ingredient is gliadin. It lowers blood glucose levels by reducing hepatic glycogen synthesis and increasing glucose uptake by muscle and adipose tissue. Often used in combination with diet and exercise, Caglione is effective in controlling blood sugar levels and reducing the occurrence of diabetes-related complications. However, there are some side effects of Cagliflozin, such as hypoglycemia and gastrointestinal discomfort, which need to be used under the supervision of a doctor.

Canagliflozin is a once-daily oral diabetes drug, belonging to a new class of selective sodiumglucoseco-transporter2 (SGLT2) inhibitors, which can block the reabsorption of blood glucose by the kidney and increase the excretion of blood glucose in urine. To lower blood sugar levels in the body. In people with type 2 diabetes, the kidneys are able to reabsorb large amounts of glucose into the bloodstream compared to people without diabetes, which can push up blood sugar levels.

Clinical Application of Canagliflozin Powder :

The target site and mechanism of action of SGLT-2 are different from those of existing oral hypoglycemic and Antidiabetic drugs, and it has creatively opened up a new pathway for glucose lowering. Its mechanism of action does not depend on pancreatic β-cells, so its efficacy is not affected by the function of pancreatic β-cells. And because its mechanism of action is not dependent on insulin, it can be used at any stage of type 2 diabetes.

Cagliflozin inhibits SLCT2, which prevents glucose in the renal tubules from being smoothly reabsorbed into the blood and excreted in the urine, thereby reducing blood glucose concentration. As glucose is excreted into the urine via the kidneys, it is accompanied by side effects such as renal impairment, symptomatic hypotension, and fungal infections. 9 clinical trials involving 10,285 patients have demonstrated the safety and efficacy of Invokana, both alone and in combination with other hypoglycemic drugs.