Fumaric Acid Raw Materials powder

CAS:110-17-8

MF:C4H4O4

MW:116.07

EINECS:203-743-0

Specification​: 99% min Fumaric Acid powder

Sample:Fumaric Acid powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Fumaric Acid powder Usage and Synthesis.

Fumaric acid is an important organic chemical raw material and fine chemical product with strong buffering properties, which can maintain the pH of aqueous solution at about 3.0.

Another major application of fumaric acid is as a pharmaceutical ingredient, in which the inhibition of the proton pump by vonoransen fumarate is reversible, whereas the inhibition of the proton pump by arazoles is irreversible.

In addition, tenofovir disoproxil fumarate (TDF) and entecavir fumarate (TAF) have similar antiviral effects in the treatment of hepatitis B. Fumaric acid also plays an important role in carbohydrate metabolism in the citric acid cycle.

Uses and functions of Fumaric Acid powder.

Used in the manufacture of unsaturated polyester resins, pesticides, acidulants, amino acids, etc.

Calibrates standard bases. Separation of thorium from cerium, lanthanum, praseodymium and rubidium. Synthetic resins. Mordant. Antioxidant.

Food acidifier, important for antibacterial, antiseptic; acidity regulator, acidifier, anti-heat oxidation additives, marinade promoter, spice. Used as solid beverage gas-producing agent for acidic substances, long-lasting and delicate bubbles; fine chemical intermediates such as pharmaceuticals and optical bleaching agents. It is used in the production of sodium dimercaptosuccinic acid, an antidote to poison, and iron rich iron for the treatment of anemia of small red blood cells. It is also used in the production of unsaturated polyester resin.

Antibutylene Succinic Acid is used in the production of unsaturated polyester resin, this kind of resin is characterized by good chemical corrosion resistance and heat resistance; Antibutylene Succinic Acid copolymer with ethylene vinyl acetate is a good adhesive, and the copolymer with styrene is the raw material for manufacturing glass fiber reinforced plastics, Antibutylene Succinic Acid is a non-toxic plasticizer, which is used for vinyl acetate latex in contact with foodstuffs.

The product is a pharmaceutical and optical bleach and other fine chemicals intermediates, in the pharmaceutical industry for the production of antidotes dimercaptosuccinic acid, transbutylsuccinic acid with sodium carbonate neutralization, that is, to obtain the sodium transbutylene ([17013-01-3]), and then replaced with ferrous sulfate to obtain transbutylsuccinic acid iron, is used to treat the treatment of anemia of microcytic blood cells type of medicine ferrous iron. The product is used as a food additive - acidifier, used in refreshing drinks, fruit candies, jellies, ice cream, etc., mostly used in conjunction with the acidifier citric acid, the monosodium salt made by the reaction of transbutyleneglycolic acid and sodium hydroxide is also used as a sour condiment, and is also used as intermediate in synthetic resins, mordants and dyestuffs.

Chemical reaction of Fumaric Acid powder.

Fumaric acid contains a conjugated maleoyl group in its molecular structure, with a carbonyl group attached to each end of the vinyl double bond, which is chemically very active. It can carry out Diels-Alder reaction; polymerization reaction (autopolymerization and copolymerization); acylation, amidation, halogenation, hydrogenation, hydration or dehydration, alkylation, free radical reaction, nucleophilic reaction and other addition reactions; isomerization reaction, transformed to maleic acid by heating to 250-300 ℃; esterification; acyl halogenation reaction, which can only generate dichloride, but can not generate mono-chloric acid; oxidation and reduction reaction. Oxidation and reduction reaction, oxidized by potassium permanganate to produce racemic tartaric acid; decomposition and decarboxylation reaction and sulfonation reaction.

Product Method of Bulk Fumaric Acid powder.

There are a number of industrial methods for the production of transbutylene succinic acid (TBSA). Its main source is the oxidation of benzene (or butene) in the presence of a catalyst to produce maleic acid (or maleic anhydride), which is then isomerized.

Benzene (or 80% of butene) is oxidized with excess air in a fluidized bed or fixed bed reactor to form maleic anhydride, which is absorbed by a circulating acid solution to form maleic acid.

After decolorization and filtration, maleic acid is isomerized under the action of thiourea catalyst, and the reactants are filtered, washed and dried to obtain transbutylene succinic acid. The isomerization catalyst is also used ammonium persulfate-ammonium bromide mixture or metal salt, amine salt, mercaptan and 10-20% hydrochloric acid. Carbohydrates such as sucrose, glucose, and maltose are also fermented by Rhizobium spp. to produce transbutylene diacid.

With sugar fermentation method, 1t products need to consume 8t of grain, the economy is very uneconomical, the domestic research to liquid paraffin instead of grain fermentation, C16-C18 content of liquid wax as a carbon source, after 80-88h of fermentation, the conversion rate of liquid wax is about 50%, the extraction rate of more than 50%.

Furfural method uses furfural as raw material, which is oxidized by sodium chlorate.