natural preservative Pimaricin Powder supplier

CAS:7681-93-8

MF:C33H47NO13

MW:665.73

EINECS:231-683-5

Specification: 99% min Pimaricin Powder

Sample:Pimaricin Powder Avaliable

Packaging:1kg/bag, 25kg/drum

Brand: Ausreson

MOQ:1KG

Appearance:white powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Pimaricin powder Usage and Synthesis.

Nathamycin is a "polyene macrolide" fungal inhibitor produced by the fermentation of Streptomyces natalis, and is currently the only internationally approved antifungal biofood preservative with high efficiency, broad-spectrum, safety and natural properties.

Natamycin relies on its lactone ring structure to interact with sterols on fungal cell membranes to form sterol compounds, thereby destroying the structure of the cytoplasmic membrane. The hydrophilic portion of the macrolide forms water pores in the membrane, impairing cell membrane permeability, which in turn causes the exudation of amino acids, electrolytes, and other substances from the fungus, and the death of the fungus.

Because, as a polyene antibiotic natamycin mechanism of action is to bind the sterols on the fungal cell membrane. The cell surface of animal organism lacks sterol, and it is not sensitive to polyene antibiotics. Therefore, natamycin is harmless to human body, and it is difficult to be absorbed by human digestive tract.

No mutagenic, carcinogenic and sensitising effects. It is a natural antifungal agent, possessing the characteristics of safety, high efficiency, natural and health.

Uses of Pimaricin.

Anti-mould agent. Good anti-mould effect when used on air-exposed food surfaces where moulds tend to proliferate. Used in fermented cheese to selectively inhibit mould proliferation and allow normal bacterial growth and metabolism.

An antifungal polyene antibiotic that inhibits fungal growth by specifically binding to ergosterol. Unlike mycobacteria and phlebotinum, natamycin does not alter the permeability of cell membranes.

How to Source and Use Pimaricin

1. Determine Suitability: Confirm that Natamycin is appropriate and approved for your specific application (food type, topical use, etc.).

2. Precise Dosing: Use micro-scale measurements. Effective concentrations are very low (e.g., 200-500 ppm for cheese surface treatment).

3. Proper Dispersion: It is not water-soluble. It must be uniformly dispersed or dissolved in an appropriate solvent (like propylene glycol) for application.

4. Consult Regulations: Adhere strictly to local (FDA, EFSA) and international regulations regarding its approved uses and maximum residual levels.

Primary Applications and Benefits

1. Food & Dairy Preservation (Primary Use): Natamycin is FDA-approved as a GRAS (Generally Recognized As Safe) substance for surface treatment of cheeses (like Gouda, Cheddar) and sausages. A tiny amount prevents mold growth without affecting taste, texture, or beneficial bacteria (unlike some chemical preservatives).

2. Targeted Topical Applications: In pharmaceutical and wellness formulations, it is used in specific creams, ointments, and eye drops to treat fungal infections, such as those caused by Candida or Aspergillus species.

3. Agricultural & Post-Harvest Use: Used to prevent fungal rot on fruits and vegetables, extending shelf life naturally.

4. Natural and Effective: For consumers and producers seeking to minimize synthetic chemicals, it offers a powerful, naturally-derived alternative for anti-fungal protection.

Product Methods of Pimaricin.

Produced by controlled fermentation of Streptomyces natalensis.

Proveedor de Pó de Pimaricina (Conservante Natural)
Поставщик порошка пимарицина (натуральный консервант)
Fournisseur de Poudre de Pimaricine (Conservateur Naturel)
Lieferant von Pimaricin-Pulver (natürliches Konservierungsmittel)
Fornecedor de Pó de Pimaricina (Conservante Natural)