Pharmaceutical Shikimic acid Raw Materials powder

CAS:138-59-0

MF:C7H10O5

MW:174.15

EINECS:205-334-2

Specification: 99% min Shikimic acid

Sample:Shikimic acid powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Shikimic acid of Usage and Synthesis.

Shikimic acid is a key ingredient in Roche's Tamiflu production. The shikimic acid currently used by Roche is extracted from star anise processing. The process of synthesis of shikimic acid from petrochemical raw materials is complicated, and there is no value of production and application except scientific research at present. Shikimic acid can be synthesized from quinic acid, another natural product, in a few steps. Quinic acid is derived from the bark of the cinchonatree tree and can be extracted and supplied in large quantities like shikimic acid.

Uses of Shikimic acid.

Shikimic acid is a key precursor in the synthesis of many alkaloids, aromatic amino acids, indole derivatives, and chiral drugs. More recently, shikimic acid has been used as A starting material for oseltamivir (the active ingredient of Tamiflu), a neuraminidase inhibitor that can be used to treat and prevent influenza A and influenza B. It is an antitumor drug, and also a synthetic raw material for antitumor drugs such as dioxamycin and glyoxalase inhibitors.

Physiological effect of Shikimic acid.

Shikimic acid affects the metabolism of arachidonic acid, inhibits platelet aggregation, inhibits arteriovenous thrombosis and cerebral thrombosis, and has anti-inflammatory and analgesic effects. It can also be used as an intermediate of antiviral and anticancer drugs, and also has the effect of preventing avian flu drugs "Tamiflu" and "anti-influenza".

Product method of Bulk Shikimic acid Powder.