Hrk supply Artemether Raw materials powder

CAS:71963-77-4

MF:C16H26O5

MW:298.37

EINECS:663-549-0

Specification: 99% min Artemether powder

Sample:Artemether powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Store at -20°C

Shelf Life: 2 Years

Test Method: HPLC

Artemether powder of Usage and Synthesis.

Clinical trials are also used in acute upper respiratory tract infection of high fever patients, symptomatic treatment, achieved good curative effect. The antipyretic effect generally begins to appear about half an hour after the intrascular injection, the body temperature gradually drops in a trapezoidal fashion, and then gradually rises about 4 to 6 hours, without the phenomenon of sudden drop in body temperature, and the antipyretic effect is stable. After intramuscular injection of this product, the patient sweating less, will not cause the elderly, children, weak patients collapse and other adverse reactions.

Uses of Artemether.

Artemether has a direct killing effect on the internal red phase of Plasmodium, but has no effect on the tissue phase. The toxicity to experimental animals is very low. It absorbs mass in the body, distributes widely, and is excreted quickly. According to the electron microscope observation, the action site of this product on Plasmodium falciparum is mainly the membrane structure, and the mechanism of its antimalarial action is believed to interfere with the function of plasmodium membrane-mitochondria. A methyl ether derivative of artemisinin.

Pharmacological action of Artemether.

This product not only has a strong killing effect on the internal asexual reproductive body of red blood cells, but also can promote the liver migration and killing of adult schistosomiasis, and is also effective on the schistosomiasis children at different developmental stages. The children who are 1 week old are the most sensitive to drugs, and the effect on female worms is more obvious than that on male worms, and the immediate effect is good.

It is suitable for all kinds of malaria, but mainly used in the treatment of chloroquine falciparum malaria and emergency treatment of dangerous falciparum malaria.

The curative effect of this product on falciparum malaria (including anti-chloroquine falciparum malaria and dangerous malaria) is better, the effect is exact, the obvious effect is rapid, the recent curative effect can reach 100%. The blood protozoa turned negative and fever subsided in most cases within 2 days after treatment. The reignition rate is 8%. Lower than artemisinin. Combined with primaquine can further reduce the reignition rate.

Product Methods of Bulk Artemether powder.