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  • Raw Materials powder tetracaine hydrochloride

    • Raw Materials powder tetracaine hydrochloride
    • Raw Materials powder tetracaine hydrochloride storehouse
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    • Raw Materials powder tetracaine hydrochloride quality testing
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    Product Overview:

    Tetracaine hydrochloride is a highly effective local anesthetic that can block nerve function reversibly. It is used in infiltration anesthesia, nerve block anesthesia, epidural anesthesia, etc. Compared with procaine, tetracaine has remarkable local anesthetic effect and has been widely used in clinic. It is found that the synthesis of p-butylaminobenzoic acid is the key step in the synthesis of tetracaine hydrochloride, which always has the disadvantages of unstable raw materials or low yield. Scientists have improved and improved this, in 1981 proposed to synthesize p-butylaminobenzoic acid by alkylation of p-aminobenzoic acid with 1-bromobutane, but because it can not avoid the generation of double butylated by-products, and the nature of the raw material itself is unstable, making this route is not suitable for industrial production.

    Raw Materials powder tetracaine hydrochloride Attributes

    tetracaine hydrochloride Raw Materials powder

    CAS:136-47-0

    MF:C15H25ClN2O2

    tetracaine hydrochloride

    MW:300.82

    EINECS:205-248-5

    Specification​: 99% min tetracaine hydrochloride powder

    Sample:tetracaine hydrochloride powder

    Packaging:1kg/bag, 25kg/drum

    Brand: Henrikang

    Appearance:white

    Storage: Cool Dry Place

    Shelf Life: 2 Years

    Test Method: HPLC

    Raw Materials powder tetracaine hydrochloride Details

    tetracaine hydrochloride powder Usage and Synthesis.

    Tetracaine hydrochloride is a kind of long-acting ester local anesthetic, which has the characteristics of strong penetration of mucosa and is suitable for surface anesthesia, and is often used in ophthalmology. After injection, the anesthetic effect appears slow (about 10 minutes), the post-absorption metabolism is also slow, and the local anesthesia time is as long as 3IJ, H,-J. Around. There were no adverse reactions such as vasoconstriction, dilated pupil and corneal injury after tetracaine hydrochloride, and the local anesthetic effect and toxicity were about 10 times greater than that of procaine. It is mainly used for surface anesthesia of the mucous membranes of the eyes, nose and throat, and rarely used for conduction anesthesia and epidural anesthesia. It is generally not used for infiltration anesthesia due to high toxicity.

    tetracaine hydrochloride powder

    Uses of tetracaine hydrochloride.

    Tetracaine hydrochloride is used for mucosal surface anesthesia, conduction anesthesia, epidural anesthesia and subarachnoid anesthesia. It is used for ophthalmic surface anesthesia without constricting blood vessels, damaging corneal epithelium and increasing intraocular pressure.

    tetracaine hydrochloride

    Drug interaction of tetracaine hydrochloride.

    one This drug can enhance the nerve blocking effect of cisatracurium, and the dosage of the latter should be reduced when combined.

    2. In combination with adrenaline, blood vessels can be constricted, blood flow is reduced, drug absorption is slowed down, and the duration of action is prolonged. However, they are not suitable for patients with heart disease, hypertension, hyperthyroidism and peripheral vascular disease.

    3. Hyaluronidase can effectively increase the diffusion of this drug, accelerate the effect of anesthesia, reduce local swelling, and prevent the formation of hematoma, however, hyaluronidase can also accelerate the absorption of this drug, resulting in increased toxic reactions of this drug.

    4. This drug is a derivative of p-aminobenzoic acid (PABA), and sulfonamides play an antibacterial role by inhibiting PABA of bacteria. When this drug is combined with sulfonamides, the antibacterial effect of the latter will be inhibited, so the two are not suitable for use.

    5. This medicine is acidic and should not be mixed with alkaline liquid. Even if it is an acidic drug, the dissociation value of the drug can be affected due to the difference in pH, so that the effect is reduced, or the onset time is delayed.

    6. Iodine preparation can cause the precipitation of this drug, so the injection site of this drug can not use iodine.

    tetracaine hydrochloride raw

    Product method of Bulk tetracaine hydrochloride.

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