Levamisole Raw Materials Powder 14769-73-4

CAS:14769-73-4

MF: C11H12N2S

MW:204.29

EINECS:238-836-5

Specification: 99% min Levamisole Powder

Sample: Levamisole Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Off-White to Pale Yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Levamisole Powder Usage and Synthesis.

Levamisole is also known as levamisole, levothiazole hook roundworm, repellent speed. For the thiimidazole of the left isomer, commonly used in its hydrochloride or phosphate, for the white or off-white crystalline powder; odourless, bitter taste, in water is very easy to dissolve, in ethanol in the hydrochloride soluble, phosphate slightly soluble. In alkaline waters are easy to decompose and fail.

Uses and functions of Levamisole.

Levamisole is commonly used for deworming various animals and is effective against both adult and larval worms. It is effective for both adult and larval nematodes. It can be used to expel eye parasites of various nematodes. For poultry can be used to expel a variety of nematodes in addition to the role of pigs can be used for nematodes, hairy round nematodes, Yangkou nematodes), wrinkled stomach parasites Ch (blood spear nematodes, Austrian nematodes) in the expulsion of ascarids, intestinal nematodes (round nematodes), on the nodule worms (oesophageal mouth nematode) and in the ureteral nephritis (toothed crown-tail nematode) is also effective. In dogs, it can be used to expel roundworms, hookworms and heartworms.

Levamisole is a broad-spectrum intestinal anthelmintic mainly used to expel roundworms and hookworms. It can improve the patient's resistance to bacterial and viral infections. It is currently used as adjuvant therapy after surgery for lung cancer, breast cancer or after chemotherapy for acute leukaemia and aggressive lymphoma. In addition, it can also be used in autoimmune diseases such as rheumatoid arthritis, lupus erythematosus, as well as epiglottitis, paediatric respiratory tract infections, hepatitis, bacillary dysentery, sores, abscesses and so on. It has been initially proved to be effective in stubborn bronchial asthma.

Pharmacological Effect of Levamisole.

Levamisole is a synthetic broad-spectrum anthelmintic, which inhibits the activity of succinate dehydrogenase in the muscle of the worm after entering the worm, so that fenugreek cannot be reduced to succinate, the sugar metabolism is impaired, the energy production is insufficient, and the worm's muscle is paralysed and expelled from the body.

Drug interactions of  Bulk Levamisole Powder.

1、Combined with thiamphenicol can treat severe hookworm infections and can improve the effect of expelling American hookworm.

2、Combined with thiabendazole, it can treat the mixed infection of intestinal nematode.

3、Combined with ethylamine citrate can treat filarial infections.

4, should not be combined with perchloroethylene to avoid increasing its toxicity.

5、It can enhance the pharmacological effect of anticoagulant bicoumarins.

6、When used together with alcohol, it has similar effect of abstinence from alcohol and sulphur.

7, and phenytoin can increase the blood concentration of the latter when taken together.