Feed Additives Raw Glycine Raw Powder

CAS:56-40-6

MF: C2H5NO2

MW:75.07

EINECS:200-272-2

Specification​: 99% min Glycine Powder

Sample:Glycine Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Glycine Powder Usage and Synthesis.

If the amount of glycine consumed by the human body is too much, not only can it not be absorbed and utilised by the human body, but also breaks the balance of amino acid absorption in the human body and affects the absorption of other amino acids, resulting in a nutritional imbalance and affecting health.

Milk beverages produced with glycine as the main raw material can easily affect the normal growth and development of adolescents and children. Density 1.1607. melting point 232~236°C (decomposition). Soluble in water, insoluble in ethanol and ether. It can act with hydrochloric acid to become hydrochloride. Exists in the sinews of dry low-grade carriers. Can be made by the action of monochloroacetic acid and ammonium hydroxide, can also be hydrolysed by gelatin, refined and obtained.

Uses and functions of Glycine.

It is used as a solvent for removing carbon dioxide in fertiliser industry. It is used as buffering agent of gold mould method, amino acid-making agent in the pharmaceutical industry, and used in the preparation of L-type dopa and other medicines, and used as flavouring agent and de-bittering agent of saccharin in the food industry, and used in the brewing, meat processing, and the preparation of refreshing beverages. In addition, it can also be used as pH adjusting agent and used in the preparation of electroplating solution.

The product is used as a solvent to remove carbon dioxide in the fertiliser industry.

In the pharmaceutical industry, it can be used as amino acid preparation, the buffer of gentamycin and as the synthetic raw material of anti-Barkinson's disease drug L-dopa, and it is the intermediate of ethyl imidazoleate, which is also a kind of auxiliary therapeutic drug itself, and it can treat the neurotic hyperacidity, and it is also effective in suppressing the hyperacidity of gastric ulcer.

In the food industry, it is used in the formulation of synthetic wine, brewing products, meat processing and refreshing beverages, and as a saccharin degassing agent. As a food additive, Glycine can be used alone as a flavouring agent, or in conjunction with Monosodium Glutamate, DL-alanine, Citric Acid, etc. It is also an intermediate of Ethyl Imidazoleate.

In other industries, it can be used as a pH regulator, added to electroplating solutions, or used as a raw material for other amino acids. It is used as a biochemical reagent and solvent in organic synthesis and biochemistry.

Pharmaceutical and pesticide intermediates, solvent for fertiliser decarbonation, electroplating solution, etc.

Characteristic of Glycine.

White monoclinic or hexagonal crystal system, or white crystalline powder. Odourless, with special sweet taste. Easily soluble in water, solubility in water: 25g/100ml at 25°C; 39.1g/100ml at 50°C; 54.4g/100ml at 75°C; 67.2g/100ml at 100°C. Extremely difficult to dissolve in ethanol, dissolved in 100g anhydrous ethanol is about 0.06g. Almost insoluble in acetone and ether.

Product Methods of Bulk Glycine Powder.

1. Strecker method reacts formaldehyde with sodium cyanide (or potassium cyanide) and ammonium chloride, while adding glacial acetic acid, crystals of methylene aminoacetonitrile are precipitated. The product is filtered and decomposed by adding ethanol in the presence of sulphuric acid to obtain aminoacetonitrile sulphate.

Then barium hydroxide was added to decompose to obtain the barium salt of glycine. Finally, a quantity of sulphuric acid is added to precipitate the barium quantitatively and filtered off. Concentrate the filtrate, leave it to cool, and precipitate the glycine crystals.

2. monochloroacetic acid method will be mixed with ammonia and ammonium bicarbonate and heated to 55 ° C, add monochloroacetic acid aqueous solution, reaction at 55 ° C for 2 h. Heating to 80 ° C to remove the residual ammonia, decolourisation with activated carbon.

Filtration, decolourisation solution with 95% ethanol to precipitate glycine crystals, filtration, washing with ethanol, drying to obtain the crude product. Dissolve the crude product with hot water, then add ethanol recrystallisation to obtain the finished product. Yield of about 42%.

3. Extracted from the silk hydrolysate will be 25kg waste silk, add 6N industrial hydrochloric acid 75L, at 110-120 ℃ heating reflux 22h, fully hydrolysed until the double urea reaction is not purple. After the end of hydrolysis, add double the volume of water, add 30-40g of powdered activated carbon per litre, stirring at 60 ℃ for 30min.

Use polyester cloth to filter out the impurities in the filter cylinder to get brown hydrolysate about 150 L. First, use activated carbon to adsorb tyrosine in the hydrolysate, and then use an ion exchange column to separate out glycine, and also can be separated to get alanine, serine.

Among the above production methods, monochloroacetic acid method is simpler, in fact, monochloroacetic acid is added to the ammonia storage tank, and glycine can be generated by leaving it at room temperature for a long time. Industrial production, with urotropin solution as the medium, from monochloroacetic acid and high concentration of ammonia at 70 ℃ reaction for 2h, by methanol (or ethanol) precipitation, refining treatment can be obtained white crystalline glycine, the yield of this method up to 92-94%, the product content of 99%.

Raw material consumption quota: monochloroacetic acid (95%) 1600kg/t, liquid ammonia 880kg/t, urotropine 350kg/t, methanol (95%) 1100kg/t. In addition, gelatin as raw material, hydrolysed, refined filtration, drying can be produced glycine.