• Human APIs PowderRespiratory Drugs Raw Material Antiviral Antibacterial Antipyretic Analgesics Antihistamine Drugs Antineoplastic Cosmetic Raw Material
  • Pharmaceutical IntermediatesPharmaceutical intermediates Nutritional Supplements Pharmaceutical raw materials
  • OEM & ODMCapsule Softgel Capsule Gummies Drop & drinks Tables
  • Veterinary raw materialsAntibacterial anti-inflammatory Respiratory Drugs Anthelmintics Antiviral drugs Feed additives
  • About UsCompany profileQualificationQuality AssuranceService teamFactory TourR&D Center
  • Raw material Megestrol Acetate Powder 595-33-5

    • Raw material Megestrol Acetate Powder 595-33-5
    • Raw material Megestrol Acetate Powder 595-33-5 storehouse
    • Raw material Megestrol Acetate Powder 595-33-5 quality testing
    • Raw material Megestrol Acetate Powder 595-33-5 quality testing
    • Raw material Megestrol Acetate Powder 595-33-5 certificate

    Product Overview:

    It is a semi-synthetic progesterone derivative with some inhibitory effect on hormone-dependent tumours.
    Its mechanism of action is the same as that of megestrol, probably through the influence on the secretion of pituitary gonadotropin, controlling the development and growth of ovarian follicles, thus reducing the production of oestrogen.

    Raw material Megestrol Acetate Powder 595-33-5 Attributes

    Raw material Megestrol Acetate Powder 595-33-5

    CAS:595-33-5

    MF:C24H32O4

    Megestrol Acetate

    MW:384.51

    EINECS:209-864-5

    Specification: 99% min Hydrocortisone Powder

    Sample: Megestrol Acetate Powder

    Packaging:1kg/bag, 25kg/drum

    Brand: Henrikang

    Appearance: White

    Storage: Cool Dry Place

    Shelf Life: 2 Years

    Test Method: HPLC

    Raw material Megestrol Acetate Powder 595-33-5 Details

    Megestrol Acetate Powder Usage and Synthesis.

    It acts on estrogen receptors, preventing their synthesis and reuse, interfering with their binding to estrogen, and inhibiting the growth of tumour cells.

    In addition, it can antagonise the glucocorticoid receptor and interfere with the interaction between steroid hormone receptors and regulatory proteins associated with cell growth and differentiation.

    Megestrol Acetate Powder

    Uses of Megestrol Acetate.

    Megestrol Acetate Tablets: used in the palliative treatment of hormone-dependent tumours, including endometrial cancer and breast cancer.

    Megestrol Acetate Dispersible Tablets: It is a semi-synthetic progesterone derivative, mainly used in the treatment of advanced breast cancer and advanced endometrial cancer, and also has some efficacy in kidney cancer, prostate cancer and ovarian cancer. It can also improve appetite and cachexia in advanced cancer patients.

    Megestrol Acetate Capsules / Megestrol Acetate Soft Capsules: It is used in the treatment of advanced breast cancer and advanced endometrial cancer, and also has some efficacy in kidney cancer, prostate cancer and ovarian cancer.

    It can also improve appetite and cachexia in patients with advanced tumours.

    Megestrol Acetate

    Pharmacological Effect of Megestrol Acetate.

    It is a semi-synthetic progesterone derivative with some inhibitory effect on hormone-dependent tumours.

    Its mechanism of action is the same as that of megestrol, probably through the influence on the secretion of pituitary gonadotropin, controlling the development and growth of ovarian follicles, thus reducing the production of oestrogen.

    It acts on estrogen receptors, preventing their synthesis and reuse, interfering with their binding to estrogen, and inhibiting the growth of tumour cells.

    In addition, it can antagonise the glucocorticoid receptor and interfere with the interaction between steroid hormone receptors and regulatory proteins associated with cell growth and differentiation.

    Megestrol Acetate CAS 595-33-5

    Product Method of Bulk Megestrol Acetate Powder.

    The 16,17α-epoxyprogesterone can be debrominated by hydrogen bromide ring-opening and nickel-catalysed reduction to produce 17α-hydroxyprogesterone, which is then acetylated and acid hydrolysed to produce 17α-acetyloxyprogesterone, and then etherified with triethyl orthoformate and reacted with Vilsmeier to obtain 3-ethoxy-6-formyl-17α-acetoxypregnan-2,5-dien-20-one, and then reduced with potassium borohydride, acid hydrolysed, dehydrated, and translocated to obtain this product.

    Our advantage
    Our Factory
    Shipping
    Tel: 86-29-89601602
    WhatsApp: 8615091775531
    WeChat: 15091775531
    E-mail: sales21@interlgroup.com
    Add: Fengcheng 2nd Road, Weiyang District, Xi'an, Shaanxi, China
    ©2023 Xi'an Henrikang Biotech Co., Ltd.,