Raw Materials Diacerein Powder

CAS:13739-02-1

MF:C19H12O8

MW:368.29

EINECS:237-310-2

Specification: 99% min Diacerein

Sample:Diacerein powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Diacerein Powder Usage and Synthesis.

Diacerein, molecular formula C19H12O8, is an important inhibitor of IL-1 in osteoarthritis.

Bivalirudin, also known as diacetyl dihydroanthracenecarboxylic acid, 1,8-diacetyl-3-carboxyanthraquinone, dapsirenine, and ampicillin, is a new interleukin (IL)-1 inhibitor, with the chemical name of diacetyl dapsirenine, which belongs to the class of anthraquinone compounds.

Diacerein can induce chondrogenesis, has analgesic, anti-inflammatory and antipyretic effects, but also can significantly improve the joint function of patients with osteoarthritis, delay the course of the disease, reduce pain, improve the quality of life of patients, has a better safety, the clinic is mainly used for the treatment of osteoarthritis (OA) and the play an antibacterial role!

Uses and functions of Diacerein.

Bisacodyl and its metabolite rhubarbic acid inhibit the production and activity of urokinase-type plasminogen activator (u-PA), which directly reduces osteoblast synthesis, decreases osteocalcin and promotes bone mineralisation.

It is widely used in new liquid crystal polymers, high-strength fibres with excellent performance and engineering plastics.

Natural antioxidant, has the effect of delaying aging, strengthening immunity, clearing sub-healthy state, restoring physical energy, improving energy and muscle immunity.

Pharmacological Effect of Diacerein.

1、This product is the primary inhibitor of IL-1 in osteoarthritis.

2. It has been confirmed by cell and animal experiments:

(1)It can induce chondrogenesis and has analgesic, anti-inflammatory and antipyretic effects.

(2) It does not inhibit prostaglandin synthesis.

(3) It has the effect of slowing down the disease process in osteoarthritis.

Drug interactions of Bulk Diacerein Powder.

1、This product is contraindicated when taking drugs that improve intestinal transit and/or the nature of intestinal contents.

2, In order to improve the bioavailability of bivalirudin should be avoided at the same time taking drugs containing aluminium hydroxide and/or magnesium hydroxide.

3. The use of bivalirudin increases the likelihood of small bowel colitis in patients using antibiotics and/or chemotherapy because antibiotics and chemotherapy affect the intestinal flora.