Parecoxib Sodium Raw Material Powder

CAS: 198470-85-8

MF: C19H19N2NaO4S

Specification​: 99% min Parecoxib Sodium Powder

Sample:  Parecoxib Sodium Powder

Brand: Henrikang

Appearance: Black Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Parecoxib Sodium Usage and Synthesis:

Parecoxib sodium is a nonsteroidal anti-inflammatory drug (NSAID) that is used for the treatment of acute pain. It is a prodrug that is rapidly converted to valdecoxib, which is a selective COX-2 inhibitor.

Parecoxib sodium is administered intravenously and is commonly used after surgery or in the management of acute pain associated with other medical conditions. It is not recommended for long-term use due to the risk of cardiovascular events such as heart attack and stroke.

Parecoxib sodium is available only by prescription and should only be used under the supervision of a healthcare provider.

Pharmacokinetics of Parecoxib Sodium:

Parecoxib is a precursor drug of vadixib, which can selectively inhibit cyclooxygenase-2 (COX-2), inhibit the conversion of arachidonic acid to prostaglandin (PG), and inhibit PG synthesis , thus exerting analgesic and anti-inflammatory effects, while the inhibition of COX-1 is not obvious, thus exerting analgesic and anti-inflammatory effects without affecting the gastrointestinal mucosa, platelets and renal function.

Clinical Application of Parecoxib Sodium:

Parecoxib Sodium drug can be very helpful for pain, inflammation and fever problems, Parecoxib Sodium Powder is generally used in clinical practice for the treatment of acute pain after moderate or severe surgery.

Parecoxib Sodium is a non-steroidal anti-inflammatory drug (NSAIDs) commonly used to relieve mild to moderate pain and inflammation, such as post-surgical pain and arthritis. It can be given by intravenous injection. Parecoxib Sodium relieves pain and reduces inflammation, but has some side effects, such as gastrointestinal bleeding and allergic reactions.