Madecassic Acid materials Madecassic Acid Powder

CAS:18449-41-7

MF:C30H48O6

MW:504.71

EINECS:240-851-7

Specification: 99% min Madecassic Acid Powder

Sample:Madecassic Acid Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Store at -20°C

Shelf Life: 2 Years

Test Method: HPLC

Madecassic Acid Powder Usage and Synthesis.

Madecassoside (MC) is the main active ingredient of triterpenoid saponin in CentellaasiaticaUrb. in the family Umbelliferae, and studies have shown that MC has a wide range of ex vivo and in vivo pharmacological activities, which can reduce the inflammatory response of collagen-induced arthritis, promote the proliferation of human fibroblasts cultured in vitro, treat or prevent proliferative scar and keloidal tumour effects and protection against myocardial ischemia-reperfusion injury.

In addition, MC also has antidepressant effects, the mechanism may be related to the reduction of brain monoamine oxidase activity; at the same time, MC also has a protective effect on the neurons of rats with acute spinal cord injury and chronic aluminium intoxication caused by dementia in mice.

Uses of Madecassic Acid.

Hydroxycitrin is one of the main active ingredients in Centella asiatica, which has a variety of efficacies and effects. It can promote wound healing, repair skin scarring, anti-sensitivity, anti-inflammatory, whitening, anti-oxidation, anti-gastric ulcer and treatment of hepatitis.

Hydroxy Centella Asiatica Glycoside can reduce the effect of scarring by decreasing the activity of the enzyme for the synthesis of scarring substances while increasing the rate of expression of proteins that inhibit the synthesis of this enzyme, thus reducing scarring.

In addition, it can effectively accelerate the production of collagen, which plays a non-negligible role in supporting the filling of subcutaneous cells, promoting the vitality of keloid fibroblasts, thus increasing the synthesis and secretion of collagen fibres and matrix components, and forming granulation tissues in conjunction with newborn capillaries, etc., to fill the wound tissue defects and create the conditions for the coverage of epidermal cells.

Hydroxy Centella Asiatica Glycoside also scavenges free radicals and has a significant inhibitory effect on the proliferation of melanocytes, significantly reducing the activity of melanin synthesising tyrosinase.

Therefore, Hydroxy Centella Asiatica Glycoside can be used in the treatment of burn scarring, skin whitening and so on.

Pharmacological Effect of Madecassic Acid.

Hydroxyasiaticoside is a chemical component present in Centella asiatica that has a variety of pharmacological effects.

Studies have shown that hydroxyl asiaticoside can inhibit scar proliferation, promote wound healing, repair skin scarring, and has antisensitising, anti-inflammatory, whitening, antioxidant, anti-gastric ulcer and hepatitis treatment effects.

In addition, hydroxyasiaticoside can inhibit Aβ-induced apoptosis of hippocampal neurons, inhibit myeloperoxidase and reduce the production of malondialdehyde, which can inhibit inflammatory reactions and reduce oxygen radical damage.

Therefore, hydroxyasiaticoside has a wide range of applications in the field of medicine.

Extraction method of Bulk Madecassic Acid Powder.