Glycyrrhizic Acid Raw Materials Glycyrrhizic Acid Powder

CAS:1405-86-3

MF:C42H62O16

MW:822.94

EINECS:215-785-7

Specification: 99% min Glycyrrhizic Acid

Sample:Glycyrrhizic Acid Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Glycyrrhizic Acid Powder Usage and Synthesis.

In food:

1. Soy sauce: glycyrrhizic acid can improve the salty taste to improve the inherent flavour of soy sauce in addition to eliminating the bitter taste of saccharin, and has a synergistic effect on chemical flavouring agents.

2. Savoury dishes: with saccharin and pickled pickles in the brine method, can eliminate the bitter taste of saccharin. In the process of pickling, it can overcome the shortcomings such as fermentation failure, discolouration and hardening that occur with less sugar.

3. Flavouring: This product can be added to pickling flavouring liquid, flavouring powder or temporary flavouring when eating and drinking, which can increase the sweetness and reduce the strange taste of other chemical flavouring agents.

4. Bean sauce: pickled herring in small sauce using this product can play a role in increasing the sweetness and make the taste uniform.

In medicine and cosmetics:

1. Glycyrrhizic acid is a natural surfactant, and its aqueous solution has weak foaming property.

2. It has AGTH-like biological activity, strong antibacterial and anti-inflammatory function, commonly used in the treatment of mucosal diseases, and can prevent dental caries and mouth ulcers when used in oral hygiene products.

3. It has a wide range of compatibility, and can be used in skin care products to enhance the efficacy of other actives in sunscreen, whitening, anti-itching, conditioning, scar healing and so on.

4. It can be used as high efficient antiperspirant in combination with heptaphyllum saponin and heptaphyllum glycoside.

Uses of Glycyrrhizic Acid.

Glycyrrhizic acid, also known as liquorice saponin, is extracted from the natural plant liquorice and is the main active ingredient of liquorice. Glycyrrhizic acid has anti-inflammatory, anti-viral and hepatoprotective detoxification and enhancement of immune function. Glycyrrhizic acid has an adrenocorticotropic hormone-like effect, which can inhibit capillary permeability and reduce the symptoms of anaphylaxis.

It can reduce serum cholestrol in hypertensive patients. Due to the glucocorticoid-like pharmacological effect of glycyrrhizic acid without serious adverse reactions, it is widely used in the clinic for the treatment of various acute and chronic hepatitis, bronchitis and AIDS. It also has the functions of anticancer and anti-cancer, interferon inducer and cellular immunity regulator.

Chemical Properties of Glycyrrhizic Acid.

Glycyrrhiza glabra is a light yellow powder with sweet taste and slightly bitter taste, containing 6%-14% glycyrrhizic acid. Pure glycyrrhizic acid is crystalline powder, taste very sweet, sweet mo for sucrose 200 ~ 250 times, sweetness retained for a long time. Melting point 212～217℃.

Soluble in hot water, insoluble in ether, insoluble in propylene glycol, ethanol. Stable to heat, alkali and salt, pH54, at 3, the solution will appear precipitation. Oral LD50 in mice is more than 10g/kg. ADI deferred determination (FAO/WHO, 1994).

Product Method of Bulk Glycyrrhizic Acid Powder.

The rhizome of licorice was dried and crushed to 0.833mm powder (retaining the fibre part), 200kg of powder and fibre were taken, 1200kg of water was added, and the extract was leached for 2h at 85-100℃.

After filtration, the filtrate was then extracted with 1000kg of water for 2h, and the filtrate was filtered and the extraction was repeated for 1 time. Combine the 3 filtrates and concentrate to ]/5 volume in an enamelled evaporator. After cooling, 95% ethanol was added to make the ethanol concentration of 65%, and it was left to stand for 24h, and filtered to remove impurities such as plant proteins and polysaccharides.

Sulfuric acid was added to the filtrate, pH was adjusted to 3, and glycyrrhizic acid precipitation was precipitated. After filtration, washing, add 3 times the acetone, heating reflux 3h, pour out the acetone extract, residue and then repeated reflux extraction 2 times.

Combined 3 times the extract, filtration and recovery of acetone, that is, wet glycyrrhizic acid, drying at 45 ℃ for 1h, slowly rising temperature to 85 ~ 95 ~ C, fast drying, rise to 100 ~ 105 ℃, baked for 5min, crushed after the finished product.