Citicoline Sodium Raw Materials Citicoline Sodium powder

CAS:33818-15-4

MF:C14H26N4O11P2.Na

MW:511.31

EINECS:251-689-1

Specification​: 99% min Citicoline Sodium powder

Sample:Citicoline Sodium powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Citicoline Sodium powder Usage and Synthesis.

Sodium cytarabine can enhance the brainstem reticular formation, especially the function of the upward reticular activation system which is closely related to consciousness, enhance the action of the pyramidal system, inhibit the action of the extrapyramidal system, and promote awakening. At the same time, it can reduce cerebral vascular resistance, increase cerebral blood flow perfusion, and promote cerebral substance metabolism.

Mainly used in the treatment of craniocerebral injury and cerebrovascular accidents caused by the sequelae of the nervous system, and can be used in the treatment of Parkinson's syndrome, Alzheimer's disease has a certain effect; used in the treatment of cerebral vascular and cardiovascular diseases; other such as slow aging, improve learning and memory, etc., also has a certain effect!

Uses and functions of Citicoline Sodium powder.

Coenzyme. For acute craniocerebral trauma and brain surgery after consciousness disorder.

Acute craniocerebral trauma and brain surgery after consciousness disorders, for hemiplegia due to cerebral stroke can gradually restore the function of the limbs, but also can be used for other acute injury to the central nervous system caused by the function and consciousness disorders, but also used for ischemic cerebrovascular disease and vascular dementia .

Cytidine 5'-di-choline phosphate (CDP-choline), which supports lecithin synthesis, is produced by choline-phosphate cytidylyltransferase EC 2.7.7.15; used to study its role in neurorehabilitation.

In vivo studies of Citicoline Sodium powder.

Citicoline is a major component of cell membrane phospholipids, a complex organic molecule composed of ribose, pyrophosphate, cytosine and choline.Citicoline is water soluble and has an oral bioavailability of >90%.

Citicoline has no mitogenic or chemotactic effect on hCMEC/D3.

However, it significantly enhances wound healing, sphere germination, and strongly induces the formation of endothelial tubular structures in the basement membrane matrix.Citicoline induces the expression of phosphorylated ERK1/2.

It protects hCMEC/D3 from cell injury/apoptosis.Citicoline induces vascular neovascularization and improves the survival of human brain microvascular endothelial cells through the p-ERK1/2 and IRS-1-related pathways.

Product Method of Bulk Citicoline Sodium powder.