Astragaloside Iv raw Materials Powder CAS 84687-43-4

CAS:84687-43-4

MF:C41H68O14

MW:784.97

EINECS:1532714-185-1

Specification​: 99% min Astragaloside Iv Powder

Sample:Astragaloside Iv Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Astragaloside Iv Powder Usage and Synthesis.

Astragaloside IV, also known as Astragaloside IV or Astragaloside, is a chemical compound with the molecular formula C41H68O14 and molecular weight 784.9702.It is found in Astragalus membranaceus, which is a common herb.

Astragaloside IV has a variety of biological activities, including antioxidant, anti-inflammatory, antitumor and immunomodulatory effects. In addition, it improves cardiovascular function and neuroprotective effects.

The physical and chemical properties of Astragaloside IV include a density of 1.39 g/cm3, a boiling point of 895.7ºC at 760 mmHg, a melting point of 295-296ºC, and a refractive index of 1.62.

Uses of Astragaloside Iv.

A major active ingredient extracted from Astragalus membranaceus has a broad application prospect, especially in cardiovascular diseases, digestive diseases, cancer and other modern high-incidence and high-risk diseases, which can be developed and utilized as a drug.

The protective effects of Astragaloside include cardiovascular system, immune system, digestive system, and nervous system, and its mechanism of action is related to the regulation of calcium homeostasis, antioxidant, anti-apoptosis, and anti-virus.

Has the ability to scavenge superoxide anion free radicals. Promote fibrinolysis and inhibit endotoxin effect. Significantly improve the deformation ability of incubated red blood cells, which may be an important mechanism of Astragalus to improve blood rheological index.

Pharmacological effectof Astragaloside Iv.

1. Hypoglycemic effect

The regulatory effects of astragaloside on hepatic glucokinase in streptozotocin and high-fat diet-induced diabetic rats were investigated in type 2 diabetic rats. The results showed that astragaloside significantly reduced the blood glucose, triglyceride (TG) and insulin levels and inhibited the related mRNA and protein expression in rats at the dosages of 25 and 50 mg/kg.

In addition, astragaloside can inhibit TNF-α-induced lipolysis of 3T3-L1 lipocytes, thereby reducing the level of free fatty acids (FFA), increasing insulin sensitivity, and playing a role in lowering blood glucose and blood lipids.

2.Anti-aging effect

The anti-aging effect of astragaloside is related to its ability to scavenge free radicals and anti-lipid peroxidation, promote protein renewal, eliminate impaired nucleic acid metabolism and promote the proliferation and apoptosis of human skin fibroblasts.

3.Promote cell proliferation

Appropriate concentration of Astragaloside can promote the rapid proliferation of chondrocytes and maintain the activity of chondrocytes, providing a new way for cartilage tissue engineering to obtain a large number of seed cells within a short period of time and maintain the activity of chondrocytes.

4.Other effects

Astragaloside plays a certain anticancer activity by inhibiting the expression of Vav3.1 gene. It inhibits the flow of calcium ions into the cell through NO-cGMP pathway, inhibits the release of intracellular calcium ions, inhibits the activity of phenylephrine and angiotensin II, and exerts a certain diastolic effect on rat aortic circumflex vessels and isolated mesenteric arteries.

Product Method of Bulk Astragaloside Iv Powder.