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L-5-methyltetrahydrofolate Raw materials Powder
Product Overview:
5-Methyltetrahydrofolate is the folate metabolic pathway that converts 5,10-methylenetetrahydrofolate to biologically functional 5-methyltetrahydrofolate.5-Methyltetrahydrofolate can further enter the methyltransfer pathway, indirectly supplying methyl for DNA methylation and protein methylation through the process of homocysteine remethylation, and keeping blood homocysteine levels at a low level. levels.
L-5-methyltetrahydrofolate Raw materials Powder Attributes
CAS:31690-09-2
MF:C20H25N7O6
MW:459.46
EINECS:203-919-7
Specification: 99% min L-5-methyltetrahydrofolate Powder
Sample:L-5-methyltetrahydrofolate Powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance:White
Storage: Store at -20°C
Shelf Life: 2 Years
Test Method: HPLC
L-5-methyltetrahydrofolate Raw materials Powder Details
L-5-methyltetrahydrofolate Powder Usage and Synthesis.
5-Methyltetrahydrofolate is the most biologically active and functional form of folic acid, the only way for folic acid to participate in physiological metabolism, and the only form of folic acid that appears to be present in animal plasma and cellular free folate.
It is mainly used as an active ingredient in pharmaceuticals and as a food additive, with applications in the prevention of fetal neural tube defects, atherosclerosis, the treatment of megaloblastic anemia, the enhancement of the therapeutic effect of pyrimidines fluoride, and the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.
Uses of L-5-methyltetrahydrofolate.
Ordinary folic acid supplements, i.e. inactive form of folic acid (folicacid), need to be converted into active form of folic acid structure (5-methyltetrahydrofolate) to play a biological role in vivo through genes and related metabolism, and the efficiency of the conversion into 5-methyltetrahydrofolate that can be absorbed by the human body is extremely low, and also prone to loss of folic acid in the raw material processing process.
Widespread research in China has shown that there is a higher percentage of mutation defects in the MTHFR (a key gene for the conversion of active folic acid in vivo) gene in China than in Europe and the United States, resulting in a failure to efficiently convert active folic acid metabolism into action and causing cellular dysfunction.
MTHFR gene mutation patients need to pay more attention to daily supplementation of active folic acid, effective absorption and utilization.
In vitro studies of L-5-methyltetrahydrofolate.
Product Method of Bulk L-5-methyltetrahydrofolate Powder.
