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Cytidine 5'-Diphosphocholine Raw materials powder
Product Overview:
Citicoline, named as Citicoline in the 2005 edition of the Chinese Pharmacopoeia, and its chemical name is choline cytidine-5'-diphosphate monosodium salt, is a precursor of lecithin biosynthesis. When brain function declines, the lecithin content in brain tissue decreases significantly.
Cytidine 5'-Diphosphocholine Raw materials powder Attributes
CAS:987-78-0
MF:C14H26N4O11P2
MW:488.33
EINECS:213-580-7
Specification: 99% min Cytidine 5'-Diphosphocholine powder
Sample:Cytidine 5'-Diphosphocholine powder
Packaging:1kg/bag, 25kg/drum
Brand: Raw materials
Appearance:white
Storage: Store at -20°C
Shelf Life: 2 Years
Test Method: HPLC
Cytidine 5'-Diphosphocholine Raw materials powder Details
Cytidine 5'-Diphosphocholine powder Classification.
It is mainly used for metabolic disorders, consciousness disorders, tremor paralysis, neurological deafness and tinnitus after craniocerebral trauma and brain surgery, as well as sleeping pill poisoning. It also has good effects on Parkinson's syndrome and hemiplegia caused by cerebral thrombosis.
Citicoline is a mononucleotide composed of nucleic acid, cytosine, pyrophosphate and choline. It is mainly used in the clinic to treat a variety of neurodegenerative diseases, such as Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, etc. Studies have also shown that citicoline can increase the brain's uptake of dopamine and glutamate, thereby improving cognitive ability.
Citicoline can also reduce the release of free fatty acids and restore the activity of mitochondrial ATPase and cell membrane Na+/K+ATPase, thereby alleviating brain damage. However, the pathophysiological mechanism of neurodegenerative diseases is very complex, involving cholinergic deficiency, glutamate excitotoxicity, neuroinflammation, immune disorders, glucose metabolism impairment and destruction of the blood-brain barrier.
Uses of Cytidine 5'-Diphosphocholine.
Used for impaired consciousness after acute craniocerebral trauma and brain surgery. Cerebral thrombosis, multiple cerebral embolism, paralysis agitans, sequelae of stroke, cerebral arteriosclerosis caused by insufficient blood supply to the brain, hypnotic drugs and carbon monoxide poisoning and various organic encephalopathy.
This product is a precursor of lecithin biosynthesis and can promote lecithin biosynthesis. This product can promote the recovery and awakening of brain function. It is suitable for impaired consciousness caused by brain trauma, sequelae of stroke, etc., and is also used for impaired consciousness caused by acute damage to the central nervous system.
Usage of Cytidine 5'-Diphosphocholine.
Product Methods of Bulk Cytidine 5'-Diphosphocholine powder.
It can be extracted from liver or yeast, or chemically synthesized. The synthetic method is to react cytosine-5'-diphosphate with ethyleneimine to form cytosine-5'-diphosphate aminoethyl ester, which is then methylated with iodomethane. It can also be obtained by directly condensing cytosine-5'-phosphoramide with phosphorylcholine ester.