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Triclosan Raw Materials powder Triclosan
Product Overview:
Triclosan is an internationally popular, highly effective and safe topical antimicrobial disinfectant that kills Staphylococcus aureus, Escherichia coli and Candida albicans, and has a disinfectant effect on pyogenic cocci and intestinal pathogenic fungi.
Triclosan Raw Materials powder Triclosan Attributes
CAS:3380-34-5
MF:C12H7Cl3O2
MW:289.54
EINECS:222-182-2
Specification: 99% min Triclosan powder
Sample:Triclosan powder
Packaging:1kg/bag, 25kg/drum
Brand: Raw Materials
Appearance:White
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Triclosan Raw Materials powder Triclosan Details
Triclosan Powder Usage and Synthesis.
Triclosan can be used in the following products: highly effective disinfectant or medicated soaps; antibacterial, deodorant and hygienic soaps; hygienic bath and antibacterial liquid detergents; antibacterial dishwashing detergents; antibacterial fabric detergents; deodorant products for armpits or feet; hygienic cleansing milks and antibacterial skin creams; antiseptic handwashing liquids; disinfectants for medical devices; wound disinfectants; air fresheners and deodorisers for refrigerators; and antimicrobial finishes for fabrics.
Uses of Triclosan.
Triclosan (Irgasan) is a broad-spectrum antimicrobial agent that inhibits type II fatty acid synthase (FAS-II) in bacteria and Plasmodium falciparum, as well as mammalian fatty acid synthase (FASN), and may also have anticancer activity.
It is used in the production of high-grade daily chemical products, disinfectants for medical and food industry instruments, and the preparation of antibacterial and anti-odour finishing agents for fabrics.
Pharmacological action of Triclosan.
Product Method of Bulk Triclosan Powder.
(1) Taking 2,4-dichlorophenol as raw material, 2,4-dichlorophenol reacts with potassium hydroxide to form potassium dichlorophenate. Then with 2,5-dichloronitrobenzene under the catalysis of copper powder, the reaction obtained 2,4,4‘-trichloro-2’-nitrodiphenyl ether. Further reduction with iron powder produces 2,4,4‘-trichloro-2’-aminodiphenyl ether, which is then diazotized and hydrolysed to give the product.
(2) Take o-methoxyphenol as raw material, potassium hydroxide powder and o-methoxyphenol (guaiacol), react to make o-methoxyphenol potassium salt. Reaction with bromobenzene methoxydiphenyl ether, chlorination through chlorine, to produce 2,4,4‘-trichloro-2’-methoxydiphenyl ether. Hydrolysis with AICI3 as catalyst to produce 2,4,4‘-trichloro-2’-hydroxydiphenyl ether.