estradiol Raw Materials powder β-Estradiol

CAS:50-28-2

MF:C18H24O2

MW:272.39

EINECS:200-023-8

Specification​: 99% min estradiol powder

Sample:estradiol powder

Packaging:1kg/bag, 25kg/drum

Brand: Raw Materials

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

estradiol powder Usage and Synthesis.

Estradiol is a white or milky white or amorphous powder, soluble in dioxane and acetone, slightly soluble in ethanol, and insoluble in water. Estradiol is an intermediate between estradiol valerate and estradiol benzoate, and is an estrogen drug. It can be used to treat functional uterine bleeding, primary amenorrhea, menopausal syndrome and prostate cancer. Estradiol can promote and regulate the normal growth of female sexual organs and secondary sexual characteristics, promote the maturity and growth of breast ducts, and help locate. Estradiol can also be used in biochemical studies.

Uses and functions of estradiol.

Estradiol can be used as an estrogen drug for functional uterine bleeding, primary amenorrhea, menopausal syndrome, and prostate cancer. It can promote and regulate the normal development of female sexual organs and secondary sexual characteristics. It can promote the development and proliferation of mammary duct, but when the dose is large, it can inhibit the release of prolactin in the anterior pituitary gland and reduce milk secretion. Can also be used for milk return. However, there may be nausea, vomiting and endometrial hyperplasia and bleeding. Use with caution in patients with liver and renal insufficiency. Do not use on breast, vulva and vaginal mucosa.

Pharmacological action of estradiol.

Product method of Bulk estradiol.

Brominated with androstene-4-ene-19-demethyl-3, 17-dione at positions 2- and 6, and then dehydrogenbrominated (eliminated) in the presence of 4-ethyl-2-methylpyridine to produce 2,4, 6-androstene-triene-19-demethyl-3, 17-dione, and then pyrolysis at high temperature to produce estradione, which was then reduced by lithium aluminum hydrogen.