(r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid

Product Name: (r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Specification​: 99% min (r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid

Test Method: HPLC

CAS: 181289-33-8

MF: C9H17NO3

Sample: (r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid Powder

Keywords: (r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid, (r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid Powder
(r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid Supplier

(r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid Powder Uses and synthesis methods:
(R)-(-)-3-(carbamoyl methyl) -5-methylhexanoic acid is solid at room temperature and pressure, soluble in dimethyl sulfoxide,N, n-dimethylformyl Chemicalbook amine and other organic solvents; It has poor solubility in ether solvents and can be used as intermediates in chiral organic synthesis. In the literature, diethyl ether is often used as a solvent for recrystallization and purification.
(r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid Powder is an intermediate in chiral organic synthesis, mainly used as a molecular framework to participate in the synthesis of chiral drug molecules and bioactive molecules. (R)-(-)-3-(carbamoyl methyl) -5-methylhexanoic acid can undergo lacamidation under appropriate conditions to produce the chiral (R) -3-isobutylglutarylimide.
For the synthesis of (R)-(-)-3-(carbamoyl methyl) -5-methylhexanoic acid, the conventional synthesis method is to start from the corresponding ester compounds and obtain the target product through the ammonia transesterification reaction under certain conditions, and then adjust the reaction system into acidity by adding acid such as hydrochloric acid. That is, you get the target product (R)-(-)-3-(carbamoyl methyl) -5-methylcaproic acid. It should be noted that the route needs heating reaction effect will be better.
Studies have shown that pregabalin may reduce the calcium-dependent release of some neurotransmitters by regulating the function of calcium channels, and play an analgesic effect. It is a structural derivative of the inhibitory neurotransmitter γ-aminobutyric acid, but it does not directly bind to γ-aminobutyric acid receptors, nor does it bind to benzodiazepine receptors. Therefore, the mechanism of action remains to be further investigated. Clinically, it is mainly used to improve neuralgia and fibromyalgia, and can also be used for the treatment of neuropathic pain.

Xi'an Henrikang Biotech Co., Ltd., has passed the National Laboratory Accreditation, ISO9001 certification, halal certification, HACCP certification, fami-qs certification, kosher certification. The company's products meet the requirements of FAO, WHO and national standards. More than 60% of the products are exported, mainly to Europe, America, Australia, Russia, Japan, South Korea, UAE and some countries and regions in Southeast Asia.