Antioxidant Benfotiamine Raw Materials powder

CAS:22457-89-2

MF:C19H23N4O6PS

MW:466.45

EINECS:245-013-4

Specification​: 99% min Benfotiamine powder

Sample:Benfotiamine powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Benfotiamine Powder Usage and Synthesis.

Fenphothiamine, a fat-soluble derivative of vitamin B1, improves the low bioavailability of water-soluble vitamin B1 and increases the concentration of thiamine in the blood and tissues, thereby improving the efficacy.

(1) For the prevention and treatment of vitamin B1 deficiency;

(2) It is used to supplement when the demand for vitamin B1 is increased and the intake from food is insufficient (fatigue, hyperthyroidism, pregnancy, lactation, strenuous physical labor, etc.);

(3) For the treatment of non-alcoholic Wernicke encephalopathy;

(4) for the treatment of beriberi;

(5) for the treatment of the following diseases, presumably related to vitamin B1 deficiency and metabolic disorders, such as: neuralgia; Muscle pain, joint pain; Peripheral neuritis, peripheral nerve paralysis; Myocardial metabolic disorders; Constipation and other gastrointestinal motor dysfunction.

Use of Benfotiamine.

Pharmacological Effect of Benfotiamine.

Fenphothiamine is a fat-soluble derivative of thiamine and has higher bioavailability than thiamine, but it must be dephosphorylated by alkaline phosphatase to become a fat-soluble precursor before it can cross the cell membrane to exert its biological effect. Clinically, it is mainly used for the treatment of diabetic complications, especially for the treatment and prevention of diabetic retinopathy. Compared with other thiamine derivatives, this product is absorbed more quickly and completely after oral administration. Phenfothiamine is absorbed into the systemic circulation and is rapidly metabolized into thiamine without increasing the concentration of the drug in the brain, while hippuric acid is produced and excreted in the urine.

Product Method of Bulk Benfotiamine Powder.