Cinchonine Raw Materials Cinchonine Powder

CAS: 118-10-5

MF: C19H22N2O

MW:294.39

EINECS: 204-234-6

Specification​: 99% min Cinchonine 

Sample: Cinchonine Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Cinchonine Powder Usage and Synthesis.

Cinchonine Powder is a quinoline-type alkaloid, a type of cinchona alkaloid, also known as cinchonine and weak cinchonine, a stereoisomer of Cinchonidine.Cinchonine CAS 118-10-5 is a more abundant alkaloid in cinchona bark other than quinine.Cinchonine Raw Material is an essential analytical reagent for the determination of tungsten ore using weight An essential analytical reagent in the determination of tungsten ore by weight analysis, Cinchonine and its derivatives are widely used in the preparation, isolation and analysis of chiral drugs and chiral intermediates.

The effect of Cinchonine Powder on tumor cell growth, followed by the determination that Cinchonine can promote tumor cell apoptosis, the above experimental results indicate that Cinchonine Raw Material can inhibit tumor cell growth, promoted early tumor apoptosis, and enhanced the expression of apoptosis-promoting factors and inhibited the expression of apoptosis-inhibiting factors. Cinchonine is expected to be used in anti-tumor applications in the future.

Application/Function of Cinchonine Powder.

The effect of cinchonine on tumor cell growth was followed by the determination that cinchonine could promote apoptosis of tumor cells. The above experimental results showed that cinchonine could inhibit tumor cell growth, promote early apoptosis of tumor, and enhance the expression of apoptosis-promoting factors and inhibit the expression of apoptosis-inhibiting factors. Cinchonidine is expected to be used in anti-tumor applications in the future. Cincinnine is a stereoisomer of cinchonidine. Antimalarial drug.

Chloramphenicol is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns.it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use.

An alkaloid derived from the bark of the cinchona tree.

It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.

Cinchonine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.

It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.

Cinchonine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

Production method of Cinchonine Powder

1.Plant sources include the bark of the red cinchona tree of the Rubiaceae family, the bark of cinchona, etc. It can also be biosynthesized and made into hydrochloride and tartaric acid salt. It has antiplasmodial and antipyretic effects.

2. Cinchona bark can be extracted to obtain alkaloids, the crude product is dissolved with nitric acid, and then precipitated with ammonia, the resulting white precipitate is cinchonine.