Haelth product Tadalafil Raw Materials powder

CAS:171596-29-5

MF:C22H19N3O4

MW:389.4

EINECS:687-782-2

Specification​: 99% min Tadalafil powder

Sample:Tadalafil powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Shelf Life: 2 Years

Test Method: HPLC

Tadalafil Powder Usage and Synthesis.

1. Block phosphodiesterase-5

Tadalafil tablets are commonly used to treat erectile dysfunction in men. Tadalafil tablet can inhibit the action of PDE-5 enzyme, and thus block the decomposition of PDE-5 enzyme to the smooth muscle of the corpus cavernosum. In this way, the degree of relaxation of the smooth muscle of the cavernous body of the penis increases, and the blood flow increases, thus promoting the erection of the penis.

2, promote nitric oxide release

Tadalafil tablets promote the release of nitric oxide. Nitric oxide can activate the activity of guanylate cyclase and increase the synthesis of cyclic guanosine phosphate in penile sponges. Cyclic guanosine phosphate can cause relaxation of the smooth muscle of the cavernous body of the penis, thereby increasing blood flow and achieving erection.

3, prolong the action time of cyclic guanosine phosphate

Tadalafil tablet can inhibit the degradation of cyclic guanosine phosphate by PDE-5 enzyme, increase the concentration of cyclic guanosine phosphate in penile sponge, and enhance its diastolic effect.

4, improve erectile hardness and durability

The action time of tadalafil tablets is longer, and the effect can be maintained for several hours. At the same time, it can also increase the hardness and durability of erection and improve the quality of sexual life.

5, enhance the response of sexual stimulation to erection

Tadalafil tablets are highly sensitive to sexual stimulation and can only work in the context of sexual stimulation. Does not spontaneously cause erection, but enhances the response of sexual stimulation to erection.

Use of Tadalafil.

Tadanafil affects PDES by inhibiting PDES. GMP degradation, so when used in combination with nitrocetacrets may cause an extreme drop in blood pressure and increase the risk of syncope. CY3PA4 inducer can reduce the abiotic availability of tadana. Combining with rifampicin, cimetidine, erythromycin, clarithromycin, itraconva, ketoconva, HVI protease inhibitor, etc., may increase the blood concentration of Tadana. Attention should be paid to adjust the dose. So far, there are no reports that the pharmacokinetic parameters of this product are affected by diet and alcohol.

Preparation of Tadalafil.

Product Method of Bulk Tadalafil Powder.