Topiramate Raw Materials Powder

CAS: 97240-79-4

MF: C12H21NO8S

MW: 339.36

EINECS: 619-263-3

Specification​: 99% min Topiramate 

Sample: Topiramate Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Supply Purity 99% Topiramate Raw Materials, High Quality Supply Topiramate Powder Factory Supply Supply Topiramate Raw Powder, Manufacturer of Supply Topiramate Raw Materials.Topiramate Raw Materials is a naturally occurring monosaccharide Tsuen dextrofructose sulphide, used more broad-spectrum antiepileptic drugs, Topiramate Raw Powder can be used to control different types of epilepsy.

Uses and functions of Topiramate Powder

The results of placebo-controlled studies have confirmed that Topiramate Raw Powder add-on therapy is efficacious and safe, and well tolerated in many types of refractory epilepsy.

Treatment with topiramate monotherapy has been initiated and has also achieved good results, with seizures disappearing completely in 62% of patients.

Topiramate Raw Powder is generally used as an adjunct to antiepileptic drugs and is effective in simple and complex seizures with generalised tonic clonic seizures, and also in the treatment of infantile spasms.

Topiramate Powder is characterised by good long-term efficacy, no significant drug resistance, and can be anti-epileptic when used alone at high doses.

Pharmacological Effects of Topiramate Raw Powder

The primary mechanism of action of topiramate is to block the spread of epileptic seizures rather than to prevent them from occurring, and TPM has been found to exert its antiepileptic effects through a variety of mechanisms:

These include:

• 1, blocking voltage-dependent sodium channels thereby reducing the duration of epileptic discharges and the number of action potentials generated by each discharge.
• 2, Antagonising erythrocyanine/AMPA-glutamate receptors.
• 3, Enhances GABA activity at the non-benzodiazepine port site of the GABA receptor.
• 4, Mildly inhibits carbonic anhydrase.
• 5, Blocks T-type calcium channels.
• 6, Blocking excitatory central neurotransmitter glutamate AMPA receptor activity.

Production method of Raw Topiramate Powder