Wholesale Bulk Raw Materials lorcaserin Powder

CAS: 616202-92-7

MF: C11H14ClN

MW: 195.69 

EINECS: 809-254-4

Specification: 99% min lorcaserin Powder

Sample: lorcaserin Powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 kg

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Last updated: April 2026

lorcaserin Powder Usage and Synthesis.

Lorcaserin is a new type of drug for the treatment of obesity, belonging to the oral effective selective 5-hydroxytryptamine 2C receptor agonist, lorcaserin hydrochloride was successfully developed by the American company Arena, and was approved by the U.S. FDA for marketing on 27th June 2012, and is used as an adjunctive treatment for overweight adults with obesity or at least 1 weight-related complication on the basis of a low-calorie diet and exercise. The drug was approved by the FDA on 27 June 2012 for use as an adjunctive therapy to low-calorie diet and exercise in overweight adults with obesity or at least 1 weight-related complication. Clinical studies have shown that the drug is effective in reducing body weight and improving obesity-related metabolic indicators in obese and overweight patients and is well tolerated. With a 100-fold higher affinity for 5-HT2c than 5-HT2B (risk of heart valve disease) and a better safety profile, lorcaserin was the first weight-loss drug approved by the FDA after 1999. Mean weight loss ranged from 3 per cent to 3.7 per cent with one year of clorcaserin treatment.

How Lorcaserin Works: The Serotonin 2C Mechanism

Lorcaserin belongs to a class of drugs known as serotonin 2C (5-HT2C) receptor agonists. Unlike older weight loss chemicals that caused heart valve issues, Lorcaserin was designed to be highly selective.

• Appetite Control: It targets the hypothalamus to signal "fullness."

• Calorie Reduction: Users naturally consume fewer calories without the "jittery" feeling of stimulants.

• Metabolic Support: Early trials showed improvements in HbA1c levels for type 2 diabetic patients.

Security of lorcaserin.

Cloracaserin is well tolerated and safe. The most common adverse reactions to cloracaserin when used in non-diabetic patients are headache dizziness fatigue nausea dry mouth and constipation. It is used in diabetic patients and common adverse reactions include hypoglycaemia headache back pain cough and fatigue. Studies have found similar rates of serious adverse reactions with lorcaserin and placebo, and lorcaserin did not increase the incidence of heart valve disease.

The incidence of depression and depressed mood after treatment with lorcaserin was low, with studies showing that lorcaserin 10mgbid, 10mgqd and placebo resulted in 1.9%, 1.1% and 1.8% depression, 0.6%, 0.9%, 0.9% and 0.9% depressed mood and 0.9%, 0.9%, 0.6%, 0.7% suicidal thoughts, respectively. This product is a pregnancy drug class X, contraindicated in pregnant women; it is not known whether this product is secreted through breast milk, and the use of this drug in breastfeeding women needs to be weighed against the advantages and disadvantages of using this drug; this product is not recommended for use in children.

Pharmacological Effects of lorcaserin.

Cloxacillin is a selective 5-hydroxytryptamine agonist at the 5-hydroxytryptamine 2C (5-HT2C) receptor, which is distributed almost exclusively within the brain. Activation of this receptor activates hunger and satiety pathways, including the pathway that induces akinesinogen, which reduces appetite.

Because of the mechanism of action of lorcaserin and the theoretical possibility of a 5-hydroxytryptamine syndrome, extra caution should be exercised when lorcaserin is used in combination with drugs that may affect the 5-hydroxytryptaminergic neurotransmitter system, including treprostinil monoamine oxidase inhibitors selective 5-hydroxytryptamine reuptake inhibitors selective 5-hydroxytryptamine and norepinephrine reuptake inhibitors tricyclic antidepressants bupropion dextromethorphan lithium tramadol and St John's wort, etc. In addition, caution is required when combining this product with substrates of CYP2D6 as it may increase exposure to this class of drugs.

FAQ: Common Questions About Lorcaserin Powder

Q1: Is Lorcaserin powder legal to buy in the UK or USA?

Currently, Lorcaserin is not FDA-approved for sale as a supplement or prescription drug. Research institutions may obtain it under strict licensing, but it is not for general consumer use.

Q2: What are the common side effects of Lorcaserin?

Reported side effects included headaches, dizziness, fatigue, and dry mouth. More serious concerns involve long-term cardiovascular and oncological risks.

Q3: Can Lorcaserin be stacked with other fat burners?

Historically, it was used alone. In 2026, many formulators have moved toward stacking natural botanical extracts like Griffonia Seed Extract (5-HTP) to support serotonin levels safely.

Оптом сырьевой порошок лоркасерина
Poudre de lorcaserine en matières premières en vrac
Lorcaserin-Pulver als Rohstoff im Großhandel
Polvo de lorcaserina como materia prima al por mayor
Pó de lorcaserina como matéria-prima a granel