High Quality Synephrine HCL Raw Powder

CAS:5985-28-4

MF:C9H14ClNO2

MW:203.67

EINECS:227-804-6

Specification: 99% min Synephrine HCL Powder

Sample: Synephrine HCL Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Synephrine HCL Powder Usage and Synthesis.

Synephrine (0.1-30 μM) acted on isolated rat aorta with potent vasoconstrictive effects in a dose-dependent manner, which were inhibited by Prazosin, BRL15572, and Ketanserin, but not by SB216641 and Propranolol, suggesting that Synephrine acts via the adrenergic alpha(1)-receptors, 5-HT(1D) receptors, and 5-HT(2A) receptors.

Although Synephrine, 1R,2S-norephedrine, and β-phenylephrine had the same Ki values for all three subtypes, only Synephrine was a partial stimulant of the α1A-AR subtype stably expressed in HEK293 cells, with maximal responses at an EC50 of 4µM,100µM, which was equivalent to 55.3% of the maximal response to L phenylephrine maximal response effect.

Uses and functions of Synephrine HCL.

Synephrine can be used as a pressure-raising drugs, for shock, for heart failure, treatment of bronchial asthma and surgery and anaesthesia at the bottom of the blood pressure, deficient and shock, body, positional hypotension, etc.; α-adrenergic receptor agonists, vasoconstrictors and so on.

1. On the cardiovascular effects of Hovenia, Hovenia decoction, Hovenia extract, Hovenia injection and its active ingredient Sinfrin hydrochloride intravenously, can significantly enhance a variety of anaesthetised dogs myocardial contractility and pumping function of the indicators, with strong heart, vasoconstriction, improve the total peripheral resistance, while the left ventricular pressure and arterial blood pressure rise effect.

Modern research has also confirmed that Hovenia cepa can concentration-dependently increase rabbit aortic tension, so that the aortic smooth muscle contraction.

2. The effect on weight loss Sinfrin HCL as a weight loss promoter, its mechanism of action is to stimulate the β-3 adrenergic receptor and lipolysis and the subsequent thermogenesis.

Most dietary supplements containing Synephrine HCL also contain other different ingredients, mainly caffeine, salicylic acid and ephedrine. The combined effect of these various chemical components can increase the weight loss benefits of Synephrine HCL.

Pharmacological Effects of Synephrine HCL.

Production method of Synephrine HCL Powder.