Purity Aescin Raw Materials Powder

CAS:6805-41-0

MF:C55H86O24

MW:1131.26

EINECS:229-880-6

Specification: 99% min Aescin Powder

Sample: Aescin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: off-white Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Aescin Powder Usage and Synthesis.

Horse Chestnut and Horse Chestnut tree extracts from plant sources, to promote the synthesis of collagen, repair damaged skin, can be highly effective in moisturising rich in flavonoids, has a natural powerful anti-ageing and anti-wrinkle effect, can improve some of the blood circulation of the skin under the eyes, and can also eliminate cellulite, dark circles and puffiness under the eyes have some effect.

Uses and functions of Aescin.

Horse chestnut saponin has anti-tissue oedema, reduces vascular permeability and prevents the accumulation of water in the tissues, and rapidly eliminates the heavy feeling and pressure caused by local oedema. It can be used in the treatment of gastric cold and pain, epigastric distension, chancre and worm pain, malaria, dysentery.

Sodium heptaphyllum saponin has anti-inflammatory, anti-exudative, increasing venous tone, improving blood circulation as well as correcting cerebral malfunction. It has obvious protective effect on cerebral oedema caused by carbon monoxide, etc. It can be used in the treatment of cerebral oedema, swelling caused by trauma or surgery, and also used in venous reflux disorders. Adverse reactions can be seen, local pain at the injection site, swelling, after hot compresses can make the symptoms disappear, occasionally allergic reactions, can be treated according to the principle of drug allergy treatment. Pregnant women are prohibited during lactation, women are prohibited in the elderly, the renal function has declined, the use of drugs should pay close attention to renal function.

In vitro studies of Aescin.

Escin effectively inhibited the proliferation of pancreatic cancer cells, however, it had little effect on normal skeletal muscle cells.Escin potentiated the proliferation inhibitory and apoptosis-inducing effects of gemcitabine in BxPC-3 and PANC-1 cells.Escin also down-regulated gemcitabine-induced activation of NF-kB and its downstream gene products in pancreatic cancer cells. activation of NF-kB and its downstream gene products induced by gemcitabine.

Applicable Dosage Forms of  Bulk Aescin Powder.