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  • Cytisine Raw Materials Powder 485-35-8

    • Cytisine Raw Materials Powder 485-35-8
    • Cytisine Raw Materials Powder 485-35-8 storehouse
    • Cytisine Raw Materials Powder 485-35-8 quality testing
    • Cytisine Raw Materials Powder 485-35-8 quality testing
    • Cytisine Raw Materials Powder 485-35-8 certificate

    Product Overview:

    Cytisine has antiarrhythmic, anti-microbial infection, anti-ulcer, elevation of white blood cells and other aspects of pharmacological effects, clinically used in the rescue of surgical trauma, war wounds and asphyxiating agents, cyanide Chemicalbook agents, anaesthetics, etc. caused by poisoning of reflex apnoea and infectious diseases, respiratory and cardiovascular activity failure, as well as shock, the state of defecation and neonatal asphyxia, and other symptoms of the treatment.

    Cytisine Raw Materials Powder 485-35-8 Attributes

    Cytisine Raw Materials Powder CAS 485-35-8

    CAS:485-35-8

    MF: C11H14N2O

    Cytisine Raw Materials

    MW:190.24

    EINECS:207-616-0

    Specification: 99% min Cytisine Powder

    Sample: Cytisine Powder

    Packaging:1kg/bag, 25kg/drum

    Brand: Henrikang

    Appearance: White Powder

    Storage: Cool Dry Place

    Shelf Life: 2 Years

    Test Method: HPLC

    Cytisine Raw Materials Powder 485-35-8 Details

    Cytisine Powder Usage and Synthesis.

    Chrysoerioline (chemical name 1,5-chorismethylene-8hydro-pyrido[1,2-alpha][1,5]diazarylene-8-one, molecular formula: C11H14N2O, molecular weight (190.24), also known as chrysoerioline, wild indigo alkaloids, chrysoerioline, belongs to quinolizidine alkaloids, is a pyridine derivative, one of the main alkaloids in the bitter pea grass, mostly distributed in the family of legume, Berberaceae plants, with anticardiac, anti-microbial infections, anti-ulcer, elevating leukocytes and other multifaceted pharmacological effects. It is one of the main alkaloids in bitter bean curd, mostly distributed in plants of Leguminosae and Berberidaceae, and has various pharmacological effects such as anti-arrhythmia, anti-microbial infection, anti-ulcer, and elevation of leukocytes, etc. It is mainly used in the treatment of reflex apnea and respiratory and cardiovascular exhaustion in infectious diseases, as well as symptoms of shock, deficient state, and asphyxiation of newborn babies when rescuing surgical traumas, battle wounds, and poisonings caused by suffocating agents, cyanide toxicants, and anaesthetics, etc.

    Cytisine Powder

    Uses and functions of Daidzein.

    Chrysin is an antiarrhythmic drug. It can reduce myocardial stress and conductivity, slow down the heart rate and inhibit myocardial contractility. It is clinically used in the treatment of tachycardia. This product has the effect of reducing myocardial stress, conductivity and contractility, slowing down the heart rate and prolonging the period of inactivity. It is mainly used for ventricular tachycardia and functional palpitations. It has a contractile effect on the uterus, and can also be used to induce labour and uterine bleeding. It is also used in the preparation of artificial hibernation therapy, such as hibernation compounds.

    Used for content determination/identification/pharmacological experiments, etc. Pharmacological effects:Used for reflex apnoea, shock and neonatal asphyxia caused by surgery and various traumas. The alkaloids also have various pharmacological effects such as antiarrhythmia, anti-microbial infection, anti-ulcer, elevation of white blood cells, etc. Especially the stronger anti-cancer activity of this class of compounds. It can be used to produce smoking cessation drugs, emergency medicine, cough medicine.

    Cytisine Raw Materials

    Pharmacological Effect of Cytisine.

    1.Respiratory effect of chrysin is similar to that of nicotine, which can reflexly stimulate respiration. When 0.02mg/kg or 1.5mg/kg was injected intravenously into the femoral vein, the anaesthetised cats were strongly stimulated by respiration, heartbeat accelerated, blood pressure rose sharply, and then returned to normal as the respiratory stimulation disappeared.The respiratory stimulation of the dose of 0.01mg/kg was not only stronger than that of the same dose of santonin, but also stronger than that of the dose of 5 times ( 0.3mg/kg). The respiratory stimulating effect of 0.01mg/Chemicalbookkg doe is not only much stronger than that of the same dose of silymarin, but also stronger than that of 5 times (0.3mg/kg) dose of silymarin.

    2.Pressurising effect on the cerebral circulation: Injecting 0.1mg/kg into the carotid artery of cats produced a pressurising effect on the cerebral circulation. This effect was inhibited by PgE1 or PgE2, but enhanced by anti-inflammatory pain.

    Cytisine CAS 485-35-8

    Preparation method of  Bulk Cytisine Powder.

    1. Extracted from the sand wintergreen seeds

    Take sand wintergreen seed dry powder 500g, with methanol 70 ℃ water bath reflux extraction 6 times, combined with methanol liquid, decompression recovery of solvents to get paste, volatile dry to constant weight, paste with hydrochloric acid treatment with acidic water, acidic water extracted with chloroform for several times to remove some of the pigment, discard the chloroform solution, and then the acidic water with sodium hydroxide to adjust the pH to 9 ~ 11, and then chloroform extraction to get this product.

    2. Extraction from poisonous beans

    (1) 1 kg of seed powder, 10% KOH solution alkaline with chloroform for percolation drop or continuous extractor to the extraction is complete. Extract recovery of chloroform, the residue add 500 ml of hydrochloric acid filtration, filtrate with activated carbon decolourisation and filtration. The adsorbed chrysophanine on the activated carbon was eluted with hot oxalic acid solution. Acid solution combined, 10% KOH solution alkaline extraction with chloroform, chloroform solution with anhydrous sodium sulfate after dehydration and concentration, in the concentrate add boiling range of 30 ~ 60 ℃ of petroleum ether, canary alkali was slightly yellowish-white precipitate precipitation precipitation, filtered at 80 ° dry.

    (2) Seed powder with benzene and petroleum ether in turn, degreased powder in the air to remove the petroleum ether, and then alkalised with 10% KOH solution, and extracted with chloroform

    (3) will be (1) method of degreasing acid solution plus Mayer's reagent, canary alkali tetraiodomercurial salt precipitation. This precipitate is fine with water, treated with sodium sulfide so that the complex salt decomposition, chrysocolla alkali free, filtered mercury sulfide precipitate, acid solution with potassium hydroxide solution alkaline, extracted with chloroform

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