Pharmaceutical raw material Ampicillin Sodium Powder

CAS:69-52-3

MF:C16H20N3NaO4S

MW:373.4

EINECS:200-708-1

Specification: 99% min Ampicillin Sodium Powder

Sample:Ampicillin Sodium Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Ampicillin Sodium Powder Usage and Synthesis.

Ampicillin sodium is a broad-spectrum penicillin, antibacterial spectrum is broader than penicillin, on some gram-negative bacilli (such as Haemophilus influenzae, Escherichia coli, Aspergillus chrysogenum) also has antibacterial activity.

The effect on gram-positive cocci is similar to that of penicillin. It can also be hydrolysed and inactivated by penicillinase produced by bacteria. It is suitable for the treatment of respiratory tract infections, urinary tract infections, gastrointestinal tract infections, skin and soft tissue infections, meningitis, septicaemia, endocarditis, etc. caused by sensitive bacteria. This product is the first choice for enterococcal infections.

Uses and functions of Ampicillin Sodium.

Mainly used for lung, intestinal, biliary tract, urinary tract and other infections and septicaemia caused by sensitive bacteria. Such as bovine pasteurellosis, pneumonia, mastitis, uteritis, pyelonephritis, calf dysentery, salmonella enteritis, etc.; equine bronchopneumonia, uteritis, adenosis, foal streptococcal pneumonia, foal enteritis, etc.pig enteritis, pneumonia, dengue, uterine inflammation, and piglets with white diarrhoea, etc.; goat mastitis, uterine inflammation, and pneumonia, etc.

Pharmacological Effect of Ampicillin Sodium.

1, ampicillin sodium is a broad-spectrum semi-synthetic penicillin. This product on the haemolytic streptococcus, streptococcus pneumoniae and do not produce penicillinase staphylococcus with strong antibacterial effect, and penicillin similar or slightly inferior to penicillin.

Ampicillin also has good antibacterial effect on Streptococcus grass green, enterococci and Listeria monocytogenes is better than penicillin.

Ampicillin has antibacterial activity against Corynebacterium diphtheriae, Bacillus anthracis, Actinobacillus spp, Haemophilus influenzae, Bordetella pertussis, Neisseria spp, and anaerobic bacteria other than Bacteroides fragilis, and part of Aspergillus chimericus, Escherichia coli, Salmonella spp, and Shigella spp. are sensitive to this product.

2、Ampicillin exerts bactericidal effect by inhibiting bacterial cell wall synthesis.

Production Method of  Bulk Ampicillin Sodium Powder.

It is obtained by salting ampicillin: Suspend ampicillin in water, adjust pH to 9 with sodium hydroxide solution, dissolve and filter. The filtrate is decolourised with activated carbon, filtered and dried at low temperature to obtain the product.