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Pharmaceutical raw material dinitolmide CAS 148-01-6
Product Overview:
Dinitropamide is a nitroanilide compound, which is a kind of anticoccidial drug with both preventive and therapeutic effects. It is effective against various types of Eimeria in chickens, especially against Eimeria toxigena and Eimeria tenderis. Mainly inhibit the first generation of schizonts, the peak period of action in the second asexual reproduction of coccidia schizonts proliferation stage (i.e., the third day after infection), at the same time on the oocysts of the ascospores formation also has a role in the inhibition of killing.
Pharmaceutical raw material dinitolmide CAS 148-01-6 Attributes
CAS:148-01-6
MF: C8H7N3O5
MW:225.16
EINECS:205-706-4
Specification: 99% min dinitolmide
Sample:dinitolmide Powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance: White Powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Pharmaceutical raw material dinitolmide CAS 148-01-6 Details
dinitolmide Usage and Synthesis.
Coccidia can produce resistance to this product, but the production rate is slow and does not affect the body to produce immunity to coccidia. The therapeutic amount has no obvious adverse effect on the development of chickens, egg production and so on.
However, the long-term use of dinitropamide in high concentration will cause drug residues, which is potentially harmful to human health.
China's Ministry of Agriculture Bulletin No. 235 stipulates that the maximum residue limit of dinitrotoluamide in terms of the total amount of proximate and metabolite is 3000ug/kg in chicken meat and 6000ug/kg in chicken liver, respectively.
Uses and functions of dinitolmide.
Against coccidiosis in chickens and turkeys. It is especially effective against the most pathogenic Eimeria toxocara in the small intestine, but is slightly less effective against Eimeria hepatica. It also has excellent effect on turkey small intestine coccidia, and can be used continuously until 16 weeks of age.
As an anti-coccidiostat, it is effective in the prevention and treatment of coccidiosis in livestock and poultry. It is effective in dosage, without any side effects, non-toxicity, stable performance, and does not decompose when added to feed.
In addition to preventing and controlling coccidiosis, it can also promote the weight growth of poultry (weight gain rate of 13.8%) and improve the feed utilisation rate. After dissolved in water, this product has a food-inducing aroma for anorexic sick chickens, and the effect of medication is excellent.
Usage and dosage: 62g of this product can be mixed in 1t of feed for chickens and other poultry, livestock feeding, halving the amount of prevention; 4g of this product dissolved in 10kg of water for chickens and other poultry, livestock drinking, halving the amount of prevention; can be used in chicken feed, the maximum dosage of 62.0g/t, prohibited during egg-laying period, the suspension of the drug for 3 days.
Pharmacological Effect of dinitolmide.
Not to be used in combination with polyethers such as hainanamycin and salinomycin. Contraindicated with Nicarbazin.
Product Method of Bulk dinitolmide.
Using o-toluic acid as raw material, 3,5-dinitro-o-toluic acid was obtained by nitration, and then the product was obtained by chlorination with dichlorosulfoxide and ammonia.