Streptomycin Sulfate Powder CAS 3810-74-0 Raw Materials

CAS: 3810-74-0

MF: C21H41N7O16S

MW: 679.65

EINECS: 223-286-0

Specification​: 99% min Streptomycin Sulfate Powder

Sample: Streptomycin Sulfate Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Streptomycin Sulfate is the sulfate form of streptomycin, an antibiotic produced in the soil by Streptomyces griseus, a genus of soil actinomycetes. Streptomycin Sulfate Powder was the first chemotherapeutic drug to be introduced with definitive efficacy against tuberculosis.

Streptomycin Sulfate Raw Materials is the first chemotherapeutic drug to be introduced with definitive efficacy against tuberculosis. Sulfate Raw Materials is the most effective and least toxic antibiotic obtained from Streptomyces for extragastrointestinal use.

Streptomycin Sulfate is a bactericidal agent, which may be effective by its direct action on bacterial ribosomes, inhibiting protein synthesis. Streptomycin Sulfate is a bacteriostatic agent, probably by its direct action on the bacterial ribosome, inhibiting protein synthesis, and acting primarily on extracellular (in-vitro) cells. Streptomycin Sulfate is a bacteriostatic agent, probably by its direct action on the bacterial ribosome, inhibiting protein synthesis, and acting primarily on extracellular (including intracavitary) Mycobacterium tuberculosis.

Uses and functions of Streptomycin Sulfate Powder.

Streptomycin sulfate is the sulfate form of streptomycin, an antibiotic produced in the soil by actinomycetes of the genus Streptomyces gray. Streptomycin was the first chemotherapeutic drug to be introduced with proven efficacy against tuberculosis. It must be injected intramuscularly, thus making its long-term use, limited.

Streptomycin is the most effective and least toxic antibiotic obtained by Streptomyces for extragastrointestinal application. It is a bactericidal agent, probably effective by its direct action on bacterial ribosomes, inhibiting protein synthesis and acting mainly on extracellular (including intracavitary) Mycobacterium tuberculosis.

Streptomycin sulfate has a strong antibacterial effect on Mycobacterium tuberculosis, most of the Gram-positive cocci (such as various streptococci) and bacilli (such as Pseudomonas aeruginosa, anaerobic bacteria) antibacterial effect is not strong, many Gram-negative bacilli have a strong antibacterial effect,

the product is effective for all kinds of cutaneous tuberculosis, there is inhibition of Mycobacterium tuberculosis reproduction and the production of toxin effect, the high concentration (>0.4 μg / mL) has a High concentration (>0.4μg/mL) has bactericidal effect.

The resistance of Mycobacterium tuberculosis to streptomycin occurs rapidly, and it is recommended to be used in combination with other anti-tuberculosis drugs.

Pharmacological Effects of Streptomycin Sulfate Powder.

Streptomycin sulfate enters into the tissues of the organism, passes through the cell membrane of the pathogenic microorganisms, combines with the special receptor protein of the 30s subunit of the ribosome of the pathogenic microorganisms, interferes with the formation of the initiation complex between the messenger ribonucleic acid and the 30s subunit,

causes the DNA to be incorrect, and also means that the amino acids which should be paired should be subjected to the competitive confrontation with the unpaired amino acids, which results in the synthesis of the non-functional proteins and the multiplexing and fragmentation of ribosomes of pathogenic microorganisms. This results in the synthesis of non-functional proteins, the splitting of pathogenic microbial polysaccharides, and the eventual destruction of synthesized proteins, resulting in the death of the pathogenic microbe.

Production method of Streptomycin Sulfate Powder.

Streptomycin Sulfate Powder is effective against Gram-positive and Gram-negative bacteria, but not as effective as Penicillin G against Gram-positive bacteria such as Streptococcus and Pneumococcus, and is ineffective against Rickettsiae, protozoa, viruses and fungi; it is also effective against Mycobacterium tuberculosis and a variety of Gram-negative bacteria such as Escherichia coli, Borrelia burgdorferi, Bacillus pellucidus, Mycobacterium influenzae, Mycobacterium dysenteriae, Mycobacterium bovis, and others.

Clinically, it is mainly used for the treatment of pulmonary tuberculosis, bone tuberculosis, lymphatic tuberculosis, intestinal tuberculosis, tuberculous meningitis caused by Mycobacterium tuberculosis, and meningitis, pneumonia, sepsis, abscess, pleurisy, peritonitis, etc. It can also be used for urinary and respiratory infections caused by sensitive strains of Mycobacterium tuberculosis. It is used in the treatment of infective endocarditis caused by tuberculosis, Brucella and non-hemolytic streptococcus, plague and rabbit fever, influenza bacillus and gram-negative bacillus infections.