Sulfamethazine Raw Materials Powder

CAS:57-68-1

MF: C12H14N4O2S

MW: 278.33

EINECS: 200-346-4

Specification​: 99% min Sulfamethazine Powder

Sample: Sulfamethazine Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Sulfamethazine Powder Usage and Synthesis.

Sulfamethazine Powder is used for the prevention and treatment of staphylococcus and Streptococcus solani infections, etc. It has an inhibitory effect on bacteria such as haemolytic streptococcus and pleurisy coccus, and is mainly used for the treatment of avian cholera

It is mainly used to treat avian cholera, avian typhoid, chicken coccidiosis and so on. Veterinary drug for analytical testing.

An antimicrobial sulfonamide; induces CYP3A4 expression, as well as acetylation via N-acetyltransferase; exhibits sex-dependent pharmacokinetics, producing metabolic changes via the male-specific isoforms of

CYP2C11 to produce metabolic changes; inhibits dihydrofolate synthase to the effect of blocking folate synthesis.

Uses and functions of Sulfamethazine Raw Materials.

Sulfamethazine Powder is a broad-spectrum bacteriostatic agent with para-aminobenzoic acid (PABA), which can act competitively with PABA on the enzyme di-folate synthase in bacteria, thus preventing PABA from acting as a

As raw materials for the synthesis of bacteria need folic acid process, reducing the amount of metabolically active tetrahydrofolate, while the latter is the bacterial synthesis of purine, thymine nuclear Chemicalbook glycoside and deoxyribonucleic acid (DNA).

The latter is required for the bacterial synthesis of purine, thymine nucleoside and deoxyribonucleic acid (DNA). Therefore, sulfadimethoxine can inhibit the growth and reproduction of bacteria. The action of sulfadimethoxine is antagonised by PABA and its derivatives (procaine, bupropion).

The effect of sulfadimethoxine is antagonised by PABA and its derivatives (procaine, bupropion), as well as by the presence of pus and the breakdown products of the tissues, which provide substances essential for bacterial growth.

Pharmacological Sulfamethazine Raw Powder.

Sulfamethazine Powder is a sulfonamide antibacterial drug, with antibacterial spectrum similar to sulfadiazine, and has antibacterial effect on non-enzymatic Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Shigella and other Enterobacteriaceae. Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella and other Enterobacteriaceae, Neisseria gonorrhoeae, Neisseria meningitidis and Haemophilus influenzae have antibacterial effect. However, the resistance of bacteria to this product However, bacterial resistance to the product has increased, especially for Streptococcus spp. and Neisseria spp. and Enterobacteriaceae.

Sulfonamides are broad-spectrum antibacterial agents, structurally similar to p-aminobenzoic acid (PABA), which can compete with PABA to act on dihydrogenase in bacteria. Sulfonamides are broad-spectrum inhibitors that are structurally similar to p-aminobenzoic acid (PABA), and can compete with PABA to act on the enzyme dihydrofolate synthase in bacteria, thus preventing the synthesis of folic acid required by bacteria from PABA as a raw material, and decreasing the amount of metabolically active tetrahydrofolate, which is a key component in the synthesis of purines, thymine and thymine by bacteria. The amount of metabolically active tetrahydrofolate, which is required for the synthesis of purines, thymine nucleosides and deoxyribonucleic acid (DNA) by bacteria, was reduced, thus inhibiting bacterial growth and reproduction.

A mixture of p-acetamidobenzenesulfonyl chloride (1.0 mmol) and cyclic amine (1.5 mmol) in water (1 mL) was stirred for 5 min and the resulting precipitate was collected by filtration. It was transferred to a round-bottomed flask and 2 mL of concentrated solution was added. hydrochloric acid and 4Chemicalbook mL of water. The reaction mixture was gently boiled at 100°C for one hour. The solution obtained in an ice bath was cooled and alkalised using saturated NaHCO3 aqueous solution. The granular precipitate was filtered, washed with water and dried in air to give the product sulfadimethoxine.

Production method of Sulfamethazine Powder.

Sulfamethazine Powder is obtained from sulfamidine by cyclisation with acetylacetone. Sulfamethazine is synthesised by reacting p-acetamidobenzenesulphonyl chloride and cyclic amines in water in a series of steps to obtain the product.

A series of steps were taken to obtain the product. Another synthesis method is to react N-acetamidosulfonylimine with sodium hydroxide, and the product is obtained after a series of steps.