Veterinary Medicine (+)-Griseofulvin Powder CAS 126-07-8 Raw Materials

CAS: 126-07-8

MF: C17H17ClO6

MW: 352.77

EINECS: 204-767-4

Specification​: 99% min Griseofulvin

Sample: Griseofulvin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Griseofulvin Powder Usage and Synthesis.

(+)-Griseofulvin Powder (griseofulvin) is a non-polyene antifungal antibiotic, Griseofulvin Powder strongly inhibits fungal cell mitosis, interferes with fungal DNA synthesis, and binds to microtubule proteins, which prevents fungal cell division. Griseofulvin Powder strongly inhibits fungal cell mitosis, interferes with fungal DNA synthesis, and binds to microtubule proteins, which prevents fungal cell division. 

Griseofulvin Raw Materials has been widely used in the treatment of fungal infections of the skin and stratum corneum, and has a strong inhibitory effect on red ringworm, tinea versicolor, and other infectious diseases. Griseofulvin Raw Materials has been widely used in the treatment of fungal infections of the skin and stratum corneum, and has a strong inhibitory effect on red ringworm, tinea versicolor, and tinea lucidum. 

(+)-Griseofulvin Powder is not only a commonly used antibiotic for the clinical treatment of fungal infections of the skin and stratum corneum, but also has been used in agriculture for the control of fungal diseases, and is particularly effective against a type of Candidiasis of apples that can be caused by Griseofulvinum corneum has been used in agriculture for the control of fungal diseases, and is particularly effective against a type of Candidiasis of apples that can be caused by infections at the time of flower pollination.

Uses and functions of Griseofulvin Powder.

In medicine, this product is indicated for the treatment of various ringworm diseases, including tinea capitis, tinea cruris, tinea corporis, tinea cruris, tinea pedis and tinea cruris. The above ringworms are caused by Serratia marcescens, Serratia marcescens, Serratia abortus, Serratia interna, etc., as well as Micrococcus oryzae, Microsporum canis, Microsporum gypsum, and Serratia floccosum, etc. This product should not be used in mild, limited cases.

This product should not be used for mild, limited superficial fungal infections and those for which topical antifungal agents have been effective. Ashwagandha is ineffective against infections of Candida spp., Histoplasma spp., Actinomyces spp., Sporothrix spp., Bacillus spp., Coccidioides spp., Nocardia spp. and Cryptococcus spp. as well as lichen planus.

In agriculture, this product was first introduced by Brian et al. (1951) to control plant diseases. According to the existing research reports, it can prevent and control melon (melon) creeping blight, creeping crack disease, watermelon wilt, anthracnose, apple blossom rot, apple cold rot, apple tree rot, cucumber downy mildew, strawberry gray mold, cucurbit blight, rose powdery mildew, chrysanthemum powdery mildew, lettuce blossom rot, tomato early blight, tulip fire blight, and other fungal diseases.

This product has inhibitory effect on various dermatophytes, including dermatophytes, dermatophytes and microsporidia. It is ineffective against lichen planus, white bead-containing fungi and bacteria. It acts as a bacteriostatic agent and is effective against fungi that grow vigorously. It is used for ringworm of the head, onychomycosis, tinea capitis, tinea pedis and tinea corporis caused by sensitive fungi.

Pharmacological Effects of Griseofulvin Powder.

Griseofulvin is an antibiotic extracted from the fermentation broth of Penicilli-um griseofulvum.

Oral absorption of this product varies with the formulation, with the microparticulate form of the drug being absorbed by 25% to 70%, and its ultra-microparticulate form being almost completely absorbed after oral administration. Eating fat may significantly increase the degree of absorption.

The serum protein binding rate of the product is about 80%. After absorption, the product can be deposited in the cuticle of the skin, hair, nail, and combined with its keratin, preventing the continued invasion of sensitive skin fungi, such as ringworm, the presence of pathogenic fungi in the superficial stratum corneum with the shedding of the skin or hair and leave the human body, only a small amount of distribution to other bodily fluids and tissues.

The product can also enter the fetal circulation and secreted from breast milk. The product is metabolized and inactivated in the liver, and the main metabolites are 6-methylchrysin and its glucuronide, with a blood elimination half-life of 14-24 hours. Less than 1% of the product is excreted in urine in its original form, and about 16% to 36% is excreted in feces in its original form.

Production method of Griseofulvin Powder.

Pure Griseofulvin is colorless crystal, neutral, insoluble in water, strong endosorption, in vitro and in vitro and between pH3.0 and 8.8 are more stable to environmental factors, and can prevent and control a variety of plant mycotic diseases.

China's production of the ashwagandha species are mainly black Penicillium and Penicillium urticae, in the medium of black Penicillium moss was proto-fuzzy, pure gray when the new culture, the old age into a dark gray, the back of the deep orange-red to orange-brown. Penicillium nettle moss yellowish green to pure bright gray, thick and dense, the back of the light turbid yellow to brownish, their aerial mycelium are very much like broom-like.