Veterinary Medicine Thiamphenicol Powder CAS 15318-45-3 Raw Materials

CAS: 15318-45-3

MF: C12H15Cl2NO5S

MW: 356.22

EINECS: 239-355-3

Specification​: 99% min Thiamphenicol 

Sample: Thiamphenicol Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Thiamphenicol Powder Usage and Synthesis.

Thiamphenicol Powder is a chloramphenicol broad-spectrum antimicrobial agent, which has a stronger effect on gram-negative than positive bacteria. Veterinary Medicine Thiamphenicol is a white to off-white crystalline powder or crystals,

which is rapidly and completely absorbed by oral Thiamphenicol is a white to off-white crystalline powder or crystals, which is rapidly and completely absorbed by oral administration, and metabolized in its original form and excreted in the urine. 

Thiamphenicol Raw Materials is mainly used in the treatment of respiratory, urinary, hepatobiliary, typhoid and other intestinal surgery, obstetrics and gynecology and pentasaccharide.

Thiamphenicol Raw Materials is mainly used in the treatment of respiratory, urinary, hepatobiliary, typhoid and other intestinal surgery, obstetrics and gynecology and pentasocial infections, especially for mild infections, especially pronounced.

Uses and functions of Thiamphenicol Powder.

Thiamphenicol is a broad-spectrum bacteriostatic agent. It has inhibitory effect on most Gram-positive and Gram-negative bacteria.

Especially for Gram-negative bacilli, such as Escherichia coli, Salmonella, Typhoid fever, aerobic bacilli, Klebsiella, Pasteurella, Brucella, dysentery bacilli, etc., Gram-positive bacteria such as Bacillus anthracis, Staphylococcus, Streptococcus, Pneumococcus, Streptococcus, enterococci, and Actinomyces, etc., which is also sensitive to it.

However, it is not as effective as penicillin and tetracycline against Gram-positive bacteria. Leptospira, some mycobacteria, some chlamydia and rickettsiae are also effective.

There is complete cross-resistance between this product and chloramphenicol, and partial cross-resistance with tetracyclines.

Chemical properties White to off-white crystalline powder or crystals. Melting point (℃) 178-180 (mixed spin), 164-166 (right spin). Uses Mainly used in the treatment of respiratory, urinary, hepatobiliary, typhoid fever and other intestinal surgery, obstetrics and gynecology and otolaryngology infections, especially for mild infections, especially the role of obvious

Pharmacological Effects of Thiamphenicol Powder.

The chemical structure is similar to that of chloramphenicol, its methyl sulfone group replaces the nitro group of chloramphenicol, thus the toxicity is reduced and its in vivo antimicrobial effect is 2.5-5 times stronger than that of chlorotoxin.

It has strong antibacterial effect on Gram-positive bacteria such as pneumococcus, hemolytic streptococcus, Gram-positive bacteria such as gonococcus, meningococcus, pulmonary bacillus,

Escherichia coli, Vibrio cholerae, dysentery bacillus and influenza bacillus, etc., and it also has certain antibacterial effect on anaerobic bacillus, rickettsiae, amoebae and so on, and its mechanism is the same as that of chloramphenicol.

Its mechanism of action is the same as chloramphenicol. It mainly inhibits the synthesis of bacterial proteins, and it is fast absorbed orally, and the blood concentration can reach the highest peak in 2 hours, with a half-life of 5 hours, which is more durable than chloramphenicol, and there is a complete cross-resistance between this product and chloramphenicol, and there is a part of cross-resistance phenomenon between this product and tetracyclines.

Production method of Thiamphenicol Powder.

Thiamphenicol also has strong immunosuppressive effect, is an excellent immunosuppressant. Its mechanism of action is significantly different from other immunosuppressive agents, and its immunosuppressive effect is several times higher than that of chloramphenicol. To reflect the transplantation and surgical

Effective prolongation agent for allogeneic homogeneous transplantation.