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Cardiovascular system
(1) Expansion of coronary arteries, improve myocardial blood supply experiments show that saffron yellow pigment has a mild excitation of the heart, reduce coronary resistance, increase coronary flow and myocardial trophic blood flow effect. Determination of mouse myocardial uptake of qub showed that saffron yellow pigment has a mild increase in myocardial nutritional blood flow in mice.
(2) Reduce blood pressure, dilate blood vessels, improve organ blood supply. Experimental studies on rats have shown that saffron yellow pigment has a significant antihypertensive effect. Safflor yellow pigment and safflor yellow pigment II, safflor yellow pigment III have the effect of improving peripheral blood circulation disorders, can make the high molecular dextrose due to the rabbit eye conjunctiva circulatory disorders of the accelerated blood flow, the number of open capillary network increased and the degree of aggregation of blood cells to reduce.
Through the inhibitory effect of safflower yellow pigment on rabbit aortic smooth muscle cell proliferation experiment, to study the relationship between the antihypertensive effect of safflower yellow pigment and vascular smooth muscle cell proliferation, the results show that: safflower yellow pigment antihypertensive effect is related to its inhibition of smooth muscle cell proliferation.
Uses of Carthamin.
Analgesic effect
Saffron yellow pigment has strong and long-lasting analgesic effect. Rheumatoid arthritis belongs to the category of "paralysis" in Chinese medicine, due to overwork and exhaustion of human body, exhaustion of positive qi, low defence function of the body or insufficient qi and blood after the disease, Tengri empty and loose wind, cold, dampness and three qi to take advantage of the deficiency to invade the human body, and the prolonged illness of the evil to stay in harming the right to the deficiency of the real and real, safflower has the efficacy of activating the blood and transforming the fetish, and it has a good therapeutic effect.
Vertebral artery-type cervical spondylosis belongs to Chinese medicine "paralysis" category, one of the causes of plasma viscosity increases, slow blood flow resulting in the brain in a long-term chronic ischaemia caused by the treatment of the appropriate activation of blood to resolve the paralysis, shu meridians and collaterals. Safflower has the function of activating blood circulation, moistening dryness, relieving pain, dispersing swelling and promoting menstruation, which can significantly improve the blood supply of vertebral artery, thus achieving the therapeutic purpose.
Anti-inflammatory effect
Saffron yellow pigment has obvious inhibitory effect on formaldehyde foot swelling in rats, and significantly inhibit histamine-induced increase in skin capillary permeability in rats, and also have obvious inhibitory effect on the formation of cotton ball carnassial in rats, which proves that SY has good anti-inflammatory effect.
Pharmacological action of Carthamin.
Safflower yellow pigment is extracted from the traditional Chinese medicine safflower, composed of a mixture of several water-soluble chalcone components, the main pharmacological active ingredient is hydroxy safflower yellow pigment A (HSYA), with the efficacy of activating the blood circulation, removing blood stasis and relieving pain. Modern pharmacological research shows that saffron yellow pigment has the effect of expanding micro arteries, increasing tissue blood perfusion flow and improving microcirculation; at the same time, it can resist platelet aggregation, reduce blood viscosity, anti-coagulation, inhibit thrombosis, and can regulate blood lipids, remove harmful oxygen free radicals, prevent over-oxidation of the cell to play the role of antioxidant, which can be applied to coronary heart disease, vascular thrombosis disease, hypertension, diabetes mellitus, and other complications. It is suitable for coronary heart disease, vascular embolism, hypertension, diabetes complications, etc.
Product Method of Bulk Carthamin Powder.
By the Asteraceae plant safflower (Carthamustinctorius) dry petals after water extraction of safflower yellow pigment residue, and then extracted with sodium hydroxide or other alkali aqueous solution, add acid precipitation, separation, filtration, drying and obtained. The yield is 0.7%~0.8% of the dried flowers. It can be added with edible dextrin and so on as carrier.
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