Dapoxetine Powder CAS 119356-77-3 Raw Materials

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Dapoxetine Powder Usage and Synthesis.

Dapoxetine Powder and clomipramine are the most widely used drugs to treat premature ejaculation. Dapoxetine CAS 119356-77-3 is currently the first and only drug approved by the FDA for the treatment of premature ejaculation. 

Dapoxetine Raw Materials are characterized by oral administration on demand, rapid onset, short half-life, rapid absorption of 1 5 hours to reach the peak, and have similar curative effects on primary and secondary PE. 

Dapoxetine Raw Materials are white crystalline powder, odorless, sweet, hygroscopic, easily soluble in water, and stable in nature.

Premature ejaculation is one of the most common male sexual dysfunctions and can have a significant impact on the self-esteem of the patient and the relationship between the couple. The most widely used drugs for premature ejaculation are tricyclic antidepressants and chlorpromazine, in addition to adrenergic receptor antagonists, benzodiazepines and gabapentin. 5-hydroxytryptamine reuptake inhibitors are the most widely used drugs for premature ejaculation, with proven efficacy and rapid research progress.

Uses and functions of Dapoxetine Powder.

Dapoxetine Powder , better known by its trade name, is the first and only drug approved by the FDA for the treatment of premature ejaculation.

It is characterized by a rapid onset of action and a short half-life, with a rapid absorption time of 1.5 hours to reach its peak, and has similar efficacy in primary and secondary PE.

Studies have shown that dapoxetine 30mg and 60mg taken 1-3h before sexual intercourse can increase the intra-penile ejaculatory latency (IELT) by 2.5-3 times in patients with premature ejaculation and 3.4-4.3 times in patients with IELT <30s, while increasing ejaculatory control, increasing satisfaction and decreasing distress.

White crystalline powder, odourless and sweet, hygroscopic, soluble in water, relatively stable in nature, melting point 175-177℃.

For the treatment of premature ejaculation and erectile dysfunction in men, more than 98% of people will naturally improve the quality of erection, the number of erections, the hardness of erection, prolong the erection time and increase the orgasm of men and women.

Pharmacological Effects of Osthole / Damiana Extract Powder.

Dapoxetine CAS 119356-77-3 is a selective 5-hydroxytryptamine reuptake inhibitor. Premature ejaculation may be caused by over-reactivity of the libido centre of the brain, leading to premature ejaculation in men. The presence of chemicals such as 5-hydroxytryptamine and dopamine in the libido centre of the brain, which transmit a strong urge to ejaculate, is interfered with by dapoxetine, Dapoxetine CAS 119356-77-3 delays the time to ejaculation.

Production method of Osthole / Damiana Extract Powder.

• There are various methods of synthesis of dapoxetine, which can be summarised in two main groups:
• The first is the non-chiral synthesis, where racemic dapoxetine or its intermediates are obtained and then split to give a single S-configuration of dapoxetine;
• The second major category is asymmetric synthesis, i.e. the synthesis of S-configuration dapoxetine, usually by metal-catalyzed or bioenzymatic methods, without splitting.

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