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Clindamycin Phosphate Powder (clindamycinphosphate) is hydrolyzed to clindamycin with antimicrobial activity after it enters into the body. Clindamycin Phosphate Raw Materials has significant antibacterial effects on gram-positive bacteria such as Aureus, Streptococcus and anaerobic bacteria in the anamorphic bacteria.
Clindamycin Phosphate Raw Materials has significant antibacterial effects on gram-positive bacteria such as Aureus, Streptococcus and anaerobic bacteria in the anamorphic bacteria of Clostridium and Clostridium species, and has no cross-allergic reaction with penicillin and cephalosporin Clindamycin Phosphate
Clindamycin Phosphate Raw Materials has significant antibacterial effect on Gram-positive bacteria such as Streptococcus aureus and anaerobic bacteria such as Clostridium perfringens. bacteria such as Clostridium perfringens and Clostridium difficile, and has no cross-allergic reaction with penicillin and cephalosporin, so it can be used for penicillin allergy. used for penicillin allergy patients.
Uses and functions of Clindamycin Phosphate Powder.
Clindamycin Phosphate is mainly used for the treatment of tonsillitis, purulent otitis media, sinusitis, acute bronchitis, acute exacerbation of chronic bronchitis, pneumonia, lung abscess, bronchodilatation and skin and soft tissue infections, such as boils, carbuncles, abscesses, cellulitis, trauma infections, burns, post-surgical infections, as well as acute urethritis of the urinary system, acute pyelonephritis, prostatitis, and so on. It is also used in osteomyelitis, sepsis, peritonitis, oral infections and so on.
Clindamycin phosphate is a chemical semi-synthetic clindamycin derivative, white or off-white crystalline powder at room temperature, odorless, bitter taste, moisture attraction. It has no antimicrobial activity in vitro, and is rapidly hydrolyzed to clindamycin after entering the organism in order to exert pharmacological effects.
Its mechanism of action, antibacterial spectrum, indications, therapeutic effects and clindamycin the same, but its fat solubility and permeability than clindamycin good, can be orally or intramuscular injection and intravenous drip drug, mainly in the liver metabolism, through the bile and fecal excretion, partially excreted from the urine.
Pharmacological Effects of Clindamycin Phosphate Powder.
Clindamycin Phosphate Powder has 4-8 times stronger antibacterial effect, good absorption, high concentration in bone tissue, and strong antibacterial activity against Gram-positive cocci and anaerobes.
Its antibacterial spectrum is as follows: Gram-positive cocci including penicillin G-resistant Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus (except Streptococcus phosphorothioicus), Streptococcus pneumoniae, Micrococcus, etc.;
Gram-positive bacilli including Clostridium, Diphtheria and so on; anaerobic bacilli including Clostridium, Anaplastic bacillus, Clostridium, Propionibacterium, Fusobacterium, and anaerobic coccus, etc..
Production method of Clindamycin Phosphate Powder.
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