Vitamin K2 Powder,Vitamin K2,Bulk Vitamin K2

CAS:11032-49-8

MF:C31H40O2

MW:444.65

EINECS:234-264-5

Specification: 99% min Vitamin K2 Powder

Sample:Vitamin K2 Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Yellow Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Vitamin K2 Powder Usage and Synthesis.

The main physiological function of vitamin K is to promote the production of prothrombinogen (coagulation factor II) by the liver, and it also regulates the formation of coagulation factors VII, IX and X. Vitamin K is also used in the treatment of blood clotting. Vitamin K deficiency prolongs the blood clotting time, and bleeding can occur in severe cases.

It has been shown that a precursor of prothrombin element exists in the liver. The synthesis of this precursor does not require vitamin K. The physiological function of vitamin K is to convert this plasminogen precursor into plasminogen, and the difference between plasminogen precursor and plasminogen has been elucidated at the molecular level.

The glutamate in the terminal amino acid residues of thrombospondin is all gamma-carboxyglutamate, whereas thrombospondin precursor is all glutamate. The glutamate in the terminal amino acid residues of the prothrombinogen precursor is all carboxylated to γ-carboxyglutamate under the influence of vitamin K. H14CO3-participation in the γ-carboxyglutamate residue was also demonstrated.

Uses and functions of Vitamin K2.

The natural vitamins are vitamin K1 and vitamin K2, which are derived from plant foods and produced by intestinal bacteria, respectively, and are fat-soluble, requiring bile to assist absorption. The synthetic ones are vitamin K3 and K4, which are water-soluble and do not require bile to assist absorption. Vitamin K is necessary for the synthesis of coagulation factors Ⅱ, Ⅶ, Ⅸ, X, thus promoting the process of coagulation. When vitamin K is deficient, the synthesis of the above coagulation factors is impaired, which affects the process of coagulation and leads to bleeding.

Vitamin K2 also has analgesic effect, the mechanism of action may be related to opioid receptors and endogenous opioid-like substances mediated.

For haemostasis: obstructive jaundice, biliary fistula, chronic diarrhoea, neonatal, preterm haemorrhage, as well as long-term application of broad-spectrum antibiotics, sulphonamides caused by secondary vitamin K deficiency, and overdose of coumarins, salicylic acid caused by haemorrhage.

Analgesia: Used for biliary colic caused by cholelithiasis and biliary roundworms. Large doses can be used to relieve"sodium dichlorvos" poisoning. Broad-spectrum antimicrobials are abused to inhibit the synthesis of vitamin K by intestinal bacteria, and in haemorrhagic diseases caused by liver diseases that reduce the synthesis of prothrombin and other coagulation factors.

Effect of Vitamin K2.

Vitamin K2 can promote the synthesis of prothrombin in the liver and regulate the synthesis of coagulation factors VII, IX and X, thereby accelerating blood coagulation. In addition, it plays an important role in the phosphorylation of glucose in cells. In some bacteria (such as mycobacteria), it can be used as a component of the respiratory chain.

Definition of  Bulk Vitamin K2 Powder.

ChEBI: Menaquinone-4 is a menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration. It has a role as a bone density conservation agent, a human metabolite, an antioxidant, an anti-inflammatory agent and a neuroprotective agent.