Ausreson Curcumin Powder 95% Organic Turmeric root Extract

CAS:458-37-7

MF:C21H20O6

MW:368.38

EINECS:207-280-5

Specification: 99% min Curcumin Powder

Sample:Curcumin Powder Avaliable

Packaging:1kg/bag, 25kg/drum

Brand: Ausreson

Appearance: orange Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

bulk Curcumin Powder Usage and Synthesis.

Kuttan, an Indian scholar, first proposed the anticancer effect of curcumin in 1985. In recent years, curcumin has been found to have an inhibitory effect mechanism on the production, proliferation and metastasis of many kinds of tumour cells.

The National Institute of Oncology of the United States listed it as the 3rd generation of tumour therapeutic drug Curcumin has been used in the treatment of tumours in the United States.

When paired with mitomycin C, it reduces the dosage of mitomycin C. At the same time, it can reduce the nephrotoxicity and myelosuppression produced by the application of mitomycin C alone, and it can improve the effect of mitomycin C in the treatment of breast cancer.

Curcumin has protective effects against various toxic substances such as carbon tetrachloride, aflatoxin B1, acetaminophen, cyclophosphamide-induced hepatic damage in vitro and in vivo, and significantly reduces alkaline phosphatase and r-glutamyl transpeptidase (r-GT) activities in animals with alcoholic liver injury (ALI), preventing the occurrence of experimental fatty liver.

Uses and functions of Curcumin.

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) ac tivity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IB kinase. Inhibits inducible nit ric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nucle ar envelope. Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease (Chem. andEng. News 90(31), 44 (2012)).

Acid-base indicator, pH 7.8 (yellow) to 9.2 (reddish brown). Chromogenic reaction measures beryllium, zirconium and magnesium, borates and reagents.

A natural phenolic, anti-tumour and anti-inflammatory substance with antioxidant properties that induces apoptosis in cancer cells.

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What are the benefits of taking curcumin?

Anti-inflammatory Properties‌: Curcumin is known for its powerful anti-inflammatory effects, which can help reduce inflammation throughout the body. This makes it a potential aid in managing conditions like arthritis and other inflammatory diseases‌.

‌Antioxidant Support‌: As an antioxidant, curcumin helps protect cells from damage caused by free radicals. This can contribute to overall cellular health and may help slow the aging process and reduce the risk of chronic diseases‌.

‌Joint Health‌: Curcumin has been shown to help reduce joint pain and stiffness, making it a popular supplement for those with arthritis or other joint conditions‌.

‌Blood Sugar Management‌: Some studies suggest that curcumin may help stabilize blood sugar levels, making it a potential aid in the management of diabetes‌.

‌Cognitive Function‌: Preliminary research indicates that curcumin may have neuroprotective effects, potentially delaying the progression of neurodegenerative diseases and improving cognitive function‌

Product Method of Bulk Curcumin Powder.

(1) water as a solvent extraction. 70-80 ℃ first 8 times the amount of 1% sodium hydroxide solution leaching 0.175-.036mm turmeric powder 60-75min, filtered filter residue and then leaching twice, the amount of solvent and time can be reduced in order of discretion; combined with the three times the filtrate, add the amount of 0.8% sodium bisulphite solution, after concentration and adjust the PH with hydrochloric acid for 3-4; static stratification and abandon the upper layer Clear liquid, the lower precipitate by filtration of semi-solid curcumin, turmeric oil and turmeric resin mixture; at 70 ℃ in 70% ethanol to dissolve the mixture, while hot and filtered to remove insoluble in ethanol turmeric resin, filtrate and then use petroleum ether extraction to separate the turmeric oil, petroleum ether phase by distillation under reduced pressure recovery of petroleum ether turmeric oil, extracted residual ethanol phase by distillation under reduced pressure curcumin, yields of up to 0.5 percent - 1.5 percent. 1.5%.

(2) Organic solvent extraction.

Curcumin is soluble in ethanol, ether, acetone or methylene chloride and other solvents, can choose one from 0.16-0.32mm turmeric powder leaching curcumin and turmeric oil, after separation and concentration of petroleum ether extraction separation of turmeric oil, extracted residual phase of curcumin by distillation under reduced pressure, the yield is generally 0.55% - 1.5%.

(3) Step-by-step extraction. At 100-105 ℃ turmeric powder steam distillation 4-6h, get turmeric oil, at 80 ℃ with 1% sodium hydroxide solution soaked slag 25min; filtration, filtrate with hydrochloric acid neutralisation acidification, and then filtered to get the curcumin crude, refined to get the finished product.

FAQ.

Q: How to select curcumin with different bioavailability technologies?

A:

Phospholipid complex: Excellent absorption, mature technology, suitable for soft and hard capsules.

Nanocurcumin: Excellent water dispersibility, rapid absorption, suitable for liquid beverages, aqueous solutions, and instant powders.

Combined with piperine: Cost-effective, time-tested solution, but note piperine may affect other drug metabolism.

We can recommend the most suitable type based on your dosage form and target cost.

Q: What is the recommended daily dose of curcumin?

A: Based on most studies, the commonly effective dose for physiological effects like anti-inflammation ranges from 500-1500 mg/day for standard curcumin. With our high bioavailability products, the effective dose required to achieve the same effect can be significantly reduced (e.g., 100-300 mg/day). The specific dosage depends on the raw material type and product positioning you choose.

Q: Is curcumin safe? Are there any side effects?

A: Curcumin is highly safe at recommended dosages. Very high doses may cause gastrointestinal discomfort in a small number of individuals. Due to curcumin's mild blood-thinning properties, individuals taking anticoagulant medications (such as warfarin) should use it under medical supervision.

Q: What are your minimum order quantity (MOQ) and sample policies?

A: Our standard MOQ is 1 kilogram. We prioritize your formulation testing and offer paid samples of 100-200 grams to clients expressing cooperation intent for your product development and evaluation.

Our Strengths.

Henrikang possesses the capability to manufacture any capsule formulation. From sourcing every ingredient in your formula to post-filling inspection, we handle the entire process at optimal pricing and fastest delivery times. With our extensive experience, we can assist you in developing new products for your target audience or discuss how to scale up production efficiently. As your partner, we are committed to achieving long-term success in capsule manufacturing.

As a leading OEM manufacturer of nutritional supplement ingredients and branded products in China, we hold certifications including ISO 22000, ISO 9001, HACCP, GMP, Halal, CE, CE-ROHS, Kosher, SGS, Intertek, Eurofins, and GMP. Our facility has successfully passed FDA inspection and completed registration.