Sucralfate Raw material Sucralfate Powder

CAS:54182-58-0

MF:C11H52Al16O75S8-16

MW:2072.71

EINECS:259-018-4

Specification: 99% min Sucralfate Powder

Sample:Sucralfate Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White

Storage: Store at -20°C

Shelf Life: 2 Years

Test Method: HPLC

Sucralfate Powder Usage and Synthesis.

Aluminium thiosulphate dissociates into octasulphate sucrose polymer in acidic environment, which can be adhered to the bottom surface of ulcers and combined with gastric mucosal protein to form a barrier to protect the gastric mucosa; it can be combined with gastric proteolytic enzyme. It can inhibit the proteolytic activity of the gastric enzyme, which has a long-lasting effect, and has the effect of neutralising the gastric acid.

Uses of Sucralfate.

Aluminium thiosulphate tablets/aluminium thiosulphate chewable tablets/aluminium thiosulphate oral suspension:

For the treatment of gastric and duodenal ulcers and gastritis.

Aluminium Thiosulphate Capsules/Aluminium Thiosulphate Granules:

Used for chronic gastritis and relief of stomach pain, heartburn sensation (heartburn) and acid reflux caused by excessive stomach acid.

Aluminium Thiosulphate Suspension Gel:

For gastric ulcer, duodenal ulcer, acute and symptomatic chronic gastritis, gastritis caused by non-steroidal anti-inflammatory drugs, oesophageal ulcer

For the treatment of gastric ulcer and duodenal ulcer, acid control and inhibition of pepsin

Aluminium thiosulphate dissociates into octasulphate sucrose polymer in acidic environment, which can be adhered to the bottom surface of ulcers and combined with gastric mucosal protein to form a barrier to protect the gastric mucosa; it can be combined with gastric proteolytic enzyme. It can inhibit the proteolytic activity of the gastric enzyme, which has a long-lasting effect, and has the effect of neutralising the gastric acid.

Pharmacological Effect of Sucralfate.

Sucralfate is a gastric mucosal protective agent. In an acidic environment, it can dissociate sucralfate complex ions, which polymerise into insoluble negatively charged colloids that can combine with positively charged protein exudates at ulcers or inflammation to form a protective film and promote ulcer healing;

Aluminium thioglycollate also has the effect of adsorbing pepsin, neutralizing gastric acid and bile acid, and can promote the synthesis of endogenous prostaglandin E as well as adsorption of epidermal growth factor, so that it is concentrated in the ulcer or inflammation, which is conducive to the regeneration of mucosa.

Drug interactions of Bulk Sucralfate Powder.

1、This product and tetracycline antibiotics can form complex salts in the body, so it can reduce the absorption and utilisation of such compounds.

2、Because this product can affect the bioavailability of certain drugs, if you need to take this product at the same time to take other drugs, please use at least two hours apart, or follow the doctor's instructions.

3、Acid making agents can affect the efficacy of this product, should not take acid making agents within half an hour of taking this product.