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Natural Pancreatin raw Materials Powder Pancreatin
Product Overview:
Pancreatic enzymes hydrolyse fats, starches and proteins. After oral administration, the capsule dissolves in the stomach, releasing hundreds of pancreatic enzyme particles with enteric coating. It avoids inactivation in the stomach and mixes well with food in the stomach and enters the duodenum synchronously with food. In the proximal part of duodenum, the particles immediately disintegrate, releasing more than 80% of the activity within 130min, ensuring the digestion and absorption of nutrients.
Natural Pancreatin raw Materials Powder Pancreatin Attributes
CAS:8049-47-6
MF:/
MW:/
EINECS:232-468-9
Specification: 99% min Pancreatin Powder
Sample:Pancreatin Powder
Packaging:1kg/bag, 25kg/drum
Brand: raw Materials
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Natural Pancreatin raw Materials Powder Pancreatin Details
Pancreatin Powder Usage and Synthesis.
Pancreatic enzymes are used for the replacement therapy of pancreatic exocrine insufficiency caused by various reasons (e.g. cystic fibrosis, chronic pancreatitis, post-pancreatic resection, post-gastrectomy, tumour-induced obstruction of pancreatic duct or common bile duct, chronic pancreatic inflammatory pain, elderly people, gastrointestinal, liver and gallbladder diseases).
This product contains trypsin, amylase and other digestive enzymes, can digest protein, starch. It can digest protein and starch, and also has a digestive effect on fat. It is used for pancreatic dysfunction, diabetic patients with dyspepsia and so on. This product in neutral or slightly alkaline when the effectiveness of the best, so more with sodium bicarbonate.
Uses of Pancreatin.
Pancreatic enzyme can be used as a digestive aid; it is mainly used for dyspepsia, loss of appetite and digestive disorders due to pancreatic diseases and dyspepsia in patients with uropathy. It is mostly taken with sodium bicarbonate or made into enteric-coated tablets; it should not be crunched when taken orally to avoid destruction by stomach acid, and should not be paired with acidic drugs. It can cause diarrhoea when as large as possible. Vomiting. Occasional sneezing. Tear, rash and other allergic symptoms should be discontinued.
Drug interactions of action of Pancreatin.
Taking it with an equal amount of sodium bicarbonate can enhance the efficacy. Cimetidine inhibits gastric acid secretion and increases pH in the stomach and duodenum, so it prevents inactivation of pancreatic enzymes and enhances the efficacy of oral pancreatic enzymes. Because all Hz receptor antagonists decrease intragastric acidity, it is hypothesised that ranitidine, famotidine and nizatidine also have this interaction with pancreatic enzymes.
A reduced dose of pancreatic enzymes may be required when combined. The activity of this drug is diminished or even inactivated by splitting in acidic solutions, so it is contraindicated to take it with acidic drugs. When this drug is combined with acarbose or miglitol, the efficacy of the latter is reduced, so concomitant use should be avoided.
Product Method of Bulk Pancreatin Powder.
Fresh pancreas of pig or cow is used as raw material, activated and extracted with dilute alcohol, the extracted liquid is precipitated, defatted and dried to obtain the product.