Raw material intermediate API Fosfomycin Calcium Powder

CAS:26472-47-9

MF: C3H5O4P.Ca

MW:176.12

EINECS:1806241-263-5

Specification: 99% min Fosfomycin Calcium Powder

Sample: Fosfomycin Calcium Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Store at -20°C

Shelf Life: 2 Years

Test Method: HPLC

Adverse reaction of Fosfomycin Calcium Powder.

Calcium Fosfomycin side effects are mainly nausea, upper and middle abdominal discomfort, loss of appetite, loose stools or mild diarrhoea. It may also lead to abnormalities such as skin rash, chemophagia and elevated alanine aminotransferase in a very small number of patients. No toxic side effects on the kidney or blood system have been observed with the use of this product.

Uses of Fosfomycin Calcium.

1. Intestinal infections: bacterial enteritis, bacillary dysentery.

2、Urinary tract infections: cystitis, pyelonephritis, urethritis.

3、Dermatological and soft tissue infections: boils, anthrax, sweating, lymphadenitis, folliculitis.4、Respiratory tract infections: nasopharyngitis, tonsillitis, bronchitis, early chronic bronchitis.5、Ophthalmology: erysipelas, dacryocystitis.

6, gynaecology: vaginitis, cervicitis

Calcium fosfomycin is an antibiotic drug used for simple lower urinary tract infections and intestinal infections due to sensitive bacteria.

Pharmacological Effect of Fosfomycin Calcium.

Calcium Fosfomycin works by inhibiting the early synthesis of the bacterial cell wall, so that the synthesis of the bacterial cell wall is inhibited and leads to its death. The antibacterial spectrum of this product is wide, and it has certain antibacterial effects on most Gram-positive and Gram-negative bacteria, the antibacterial spectrum of this product includes S. aureus, E. coli, E. dysenteriae, Serratia spp., Shigella spp., Pseudomonas aeruginosa, Klebsiella pneumoniae, and Enterobacter aerogenes.

Drug interactions of Bulk Fosfomycin Calcium Powder.

1、Combined with β-lactams, it has synergistic effect on Pseudomonas aeruginosa and Pseudomonas aeruginosa (including methicillin-resistant Pseudomonas aeruginosa).

2、Combined with aminoglycosides, it has synergistic effect.

3、No cross-resistance with other antibiotics.