Robenidine Hcl raw material Robenidine Hcl Powder 25875-50-7

CAS:25875-50-7

MF:C15H14Cl3N5

MW:370.66

EINECS:247-307-8

Specification: 99% min Robenidine Hcl Powder

Sample:Robenidine Hcl Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Yellow Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Robenidine Hcl Powder Usage and Synthesis.

Chlorpheniramine Hydrochloride is a highly effective anticoccidial drug with preventive and therapeutic effects on zoonotic toxoplasmosis. It has good palatability and good effect on acute or chronic coccidiosis of chickens and rabbits.

It also has preventive and therapeutic effects on zoonotic toxoplasmosis, featuring broad-spectrum, high efficiency, low toxicity, large safety range, good palatability and promotion of growth and development.

It can obviously improve the weight gain rate and feeding remuneration of rabbits and poultry. In aquatic fisheries feeding anti-disease fattening effect is obvious. It is suitable for rural scale breeding and planting development.

Uses and functions of Robenidine Hcl.

Chlorpheniramine is a low-toxicity and high-efficiency anticoccidial drug, which can be used in chicken feed at a dosage of 30-36g/t, prohibited during egg-laying period, with a withdrawal period of 7 days; it can also be used in rabbit feed at a dosage of 50-66g/t, prohibited during pregnancy, with a withdrawal period of 7 days.

It is a new type of high efficient anticoccidial drug with high efficacy, low toxicity and good palatability. It has good effect on acute or chronic chicken coccidiosis. It can significantly improve the weight gain rate and feeding remuneration of rabbits and poultry. This product is included in the Veterinary Pharmacopoeia of the People's Republic of China (90th edition, a).

As an antibacterial agent, it is effective against staphylococcus and haemolytic streptococcus. It is mainly used for the treatment of avian cholera, avian typhoid fever, chicken autumn worm disease, etc.

Anti-coccidiosis drug, it has good effect on acute or chronic many kinds of chicken coccidiosis.

Pharmacological Effect of Robenidine Hcl.

Chlorphenylguanidine hydrochloride is a guanidine derivative. The anti-coccidial mechanism is to affect the adenosine triphosphate, interfering with the protein metabolism of coccidia, and has been widely used in the prevention and treatment of avian and rabbit coccidiosis.

The peak action of chlorproguanidine hydrochloride on coccidia is mainly in the 1st generation of schizonts (i.e., day 2 of the life cycle of coccidia). It prevents the formation of schizonts from schizonts.

It has also been shown to inhibit the 2nd generation of schizonts and even the development of oocysts.

The main mechanism of action is to inhibit oxidative phosphorylation in the worm, which depletes the energy supply of the worm and inhibits the growth and reproduction of schizonts. Coccidia are slow to develop resistance to chlorproguanil, and remain effective against strains resistant to other anticoccidials.

Chlorbenzylguanidine is effective against soft, stacked, giant, toxigenic, and slow and Eimeria burgdorferi coccidia.

Product Method of Bulk Robenidine Hcl Powder.

Aminothiourea is produced by the addition and rearrangement of sodium thiocyanate with water and hydrazine. It is then methylated with dimethyl sulphate and hydrazinolised to N.N'-diaminoguanidine sulphate. N.N'-diaminoguanidine hydrochloride is then substituted with calcium chloride. Finally condensed with p-chlorobenzaldehyde in ethanol to produce chlorphenylguanidine hydrochloride in 94% yield.