Melatonin Raw Materials Powder

CAS:73-31-4

MF:C13H16N2O2

MW:232.28 

EINECS:200-797-7

Specification: 99% min Melatonin Powder

Sample: Melatonin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Melatonin Powder Usage and Synthesis.

Melatonin (MT) is a hormone secreted by the pineal gland of the brain. Melatonin belongs to the indole heterocyclic compound, its chemical name is n-acetyl-5 methoxyl colorAmine, also known as pineal hormone, melatonin, melatonin. After melatonin is synthesized and stored in the pineal body, sympathetic nerve excitation innervates pineal cells to release melatonin.
The secretion of melatonin has an obvious circadian rhythm, which is suppressed during the day and active at night. Melatonin can inhibit the hypothalamic-pituitary-gonadal axis and reduce the contents of gonadotropin releasing hormone, gonadotropin, luteinizing hormone and follicle stimulating hormone, and can directly act on the gonads to reduce the contents of androgen, estrogen and progesterone. In addition, MT has strong neuroendocrine immunomodulatory activity and scavenging free radical antioxidant capacity, which may become a new method and approach for antiviral therapy. MT is eventually metabolized in the liver, and damage to liver cells can affect the level of MT in the body.

Uses and functions of Melatonin

Melatonin is a hormone produced by the pineal gland. Melatonin is highly conserved and is a non-receptor free radical scavenger and a broad-spectrum antioxidant. Melatonin helps prevent ischemia-reperfusion damage to the liver, brain, heart muscle, intestines, and kidneys.Melatonin can be widely used in health food, medicine, all kinds of cosmetics, nourishing and nursing products.

Function:

Melatonin freckle, natural whitening: melatonin can make the skin white. It can regulate the endocrine of the human body, remove dark spots, age spots, melasma, pregnancy spots and pigmentation caused by sun radiation, whitening and moisturizing the skin, and restoring the youthful style.

Effectively improve sleep: proper supplementation of melatonin can effectively improve sleep quality.

Prolong life: Melatonin is the most important high-efficient endogenous antioxidant in the brain and has a protective effect on the brain. Therefore, melatonin is an important anti-aging hormone. Maintain and enhance sexual function: supplementing melatonin can improve sexual function of middle-aged and elderly people who are aging and have decreased energy, which leads to decreased sexual desire.  

Physiological function of Melatonin.

The well-known function of melatonin is mainly to improve sleep quality (dosage 0.1-0.3mg), shorten the waking time and falling asleep time before going to bed, improve sleep quality, significantly reduce the number of awakenings during sleep, the light sleep stage is short, the deep sleep stage is prolonged, and the wake threshold decreases the next morning. It has a strong function of adjusting the time difference.The biggest feature of melatonin should be that it is the strongest endogenous free radical scavenger ever discovered. The basic function of melatonin is to participate in the antioxidant system and prevent oxidative damage to cells. In this regard, its efficacy exceeds that of all known substances in the body. The latest research proves that MT is the endocrine commander-in-chief, which controls the activity of various endocrine glands in the body. Thereby indirectly controlling the functions of our whole body. 

Production method of Melatonin Powder.

Melatonin is present in the pineal gland of dry mammalian brain. In general, the pineal gland of bovine brain is freeze-dried, ground into powder, and then the fat is removed with petroleum cake. After centrifugation, the supernatant is taken and extracted with equal volume of ethyl acetate. After vacuum drying, the white melatonin crude product was obtained, and then the fine product was obtained after recrystallization.