Bulk Raw Materials Nuciferine Powder

CAS:475-83-2

MF:C19H21NO2

MW:295.38

EINECS:-

Specification: 99% min Nuciferine Powder

Sample: Nuciferine Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White to Light Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Nuciferine Powder Usage and Synthesis.

Huperzine is a kind of health care ingredient which is widely used in lipid-lowering, blood pressure-lowering, fat elimination, etc. It is also praised by the western authoritative medical society as "the holy product of lipid-lowering", and almost 80% of the weight-loss health care products manufacturers in China will add the low concentration of common Huperzine, which is to ensure the weight-loss effect.

Uses and functions of Nuciferine.

1. Huperzine contains a variety of effective lipid alkaloids, which can effectively break down body fat and expel it out of the body strongly.

2. Huperzine can form a layer of fat barrier on the intestinal wall of the human body, preventing fat absorption and accumulation of fat.

3. Hollandine detoxification effect is remarkable, can effectively open up all kinds of metabolic pathways in the body, remove free radicals, mediate the function of internal organs.

4. Huperzine has the effect of clearing heart fire, calming liver fire, diarrhoeing spleen fire, lowering lung fire and clearing heat and nourishing the spirit, mediating the endocrine system and improving the microcirculation of the human body.

5. lotus leaf alkali to improve greasy eating habits, which has a strong fat rejection effect, lotus leaf alkali long-term accumulation of human body, inhibit fat absorption, will produce subliminal signals inertia brain dietary nerves, so that you gradually produce aversion to meat and greasy food!

Pharmacological Effect of Nuciferine.

Folding Lipid Lowering Health Care

Due to the insulin insensitivity of obese human body cells, patients with glucose tolerance is often reduced, total lipids, cholesterol, triglycerides and free fatty acids are often increased, presenting hyperlipidaemia and hyperlipoproteinaemia, which is the basis for the induction of diabetes mellitus, atherosclerosis, coronary heart disease, cholelithiasis, hypertension and other diseases, lotus leaf alkaloids can effectively decompose and reduce the body cell fat, improve its insulin perception, and put an end to the occurrence of high-fat diseases.

In vitro studies of  Bulk Nuciferine Powder.

In rodent models relevant to antipsychotic drug action, Nuciferine blocks head-twitch responses and discriminative stimulus effects ofa 5-HT 2A agonist, substituted for clozapine discriminative stimulus, enhanced amphetamine induced locomotor activit, inhibited phencyclidine (PCP)-induced locomotor activity, and rescued PCP-induced disruption of prepulse inhibition without induction of catalepsy. in the presence of 1 or 3 mg/kg Nuciferine, cumulative PCP doses produce similar substitution to PCP alone. in the clozapinetrained animals, a dose-dependent substitution for 1.25 mg/kg clozapine is seen at 10 mg/kg Nuciferine (80.63% drug lever responding), with an ED so value of 5.42 mg/kg (95% Cl 3.09-9.48 mg/kg) while the lower doses tested (0.1 mg/kg-3 mg/kg) fails to producesubstitution for clozapine's discriminative cue. In addition to a high percentage of responding on the clozapine-appropriate lever, 10 mgikg Nuciferine also produces significant rate suppression as compared to vehicle control points (p<0.001).