Diosmin Raw Materials Powder

CAS:520-27-4

MF: C28H32O15

MW: 608.54

EINECS:208-289-7

Specification​: 99% min DiosminPowder

Sample: Diosmin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Pale Beige to Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Diosmin Powder Usage and Synthesis.

As one of the commonly used vasoprotective drugs, Diosmin is often used in the treatment of various peripheral vascular diseases. Clinical studies have shown that Diosmin can improve the circulation of blood and lymphatic fluids, reduce oedema, and it is often used in the treatment of the following four diseases in modern clinics.

1, varicose veins of the lower limbs: clinical research shows that Diosmin can effectively improve the clinical symptoms of patients with varicose veins of the lower limbs, reduce pain, activity inconvenience, relieve venous stasis of the lower limbs, improve venous return.

2, acute or chronic haemorrhoids: clinical studies have shown that for patients with chronic haemorrhoids, Diosmin can effectively improve the size of their haemorrhoids, reduce the number of bleeding and anal prolapse, and effectively prevent and treat their acute attacks; secondly, for patients with acute haemorrhoidal attacks, the application of Diosmin on the basis of haemostatic and other symptomatic treatments can quickly control bleeding and reduce perianal pain, thus effectively alleviating the patient's pain and improving the prognosis. Improve the prognosis.

3、Lymphatic reflux disorder, lymphoedema: Diosmin can effectively improve lymphatic reflux and reduce limb swelling. Clinical studies have shown that after taking Diosmin, patients with lymphoedema will have a significant reduction in limb swelling and pain, making lymphatic circulation smooth and improving patients' quality of life and health.

4, peripheral skin ulcers: clinical studies have shown that on the basis of promoting skin healing treatment, with the use of Diosmin, can effectively accelerate the prognosis of skin wounds or ulcers, reduce the local inflammatory response, alleviate skin pain, thereby effectively improving the prognosis of the disease.

Uses and functions of Soy Isoflavone.

1.Enhancement of venous tensionDiosmin enhances venous wall tension, even in high temperature, it causes stronger contraction of veins than other drugs such as rutin, and still enhances the tension of veins in the case of body acidosis. Diosmin has specific affinity for veins without affecting the arterial system.

2. Improve microcirculation, Diosmin can significantly reduce the adhesion of leukocytes and vascular endothelial cells, migration, disintegration and release of inflammatory substances, such as histamine, bradykinin, complement, leukotrienes, prostaglandins and excessive free radicals, etc., so as to reduce the permeability of the capillaries and enhance their tension, Diosmin also has the function of reducing blood viscosity and enhancing the flow rate of erythrocytes, so as to reduce the stagnation of the microcirculation.

3.Promote lymphatic drainageDiosmin increases the speed of lymphatic drainage.

Pharmacological Effects of Diosmin.

Diosmin, also known as Avellan, is a medicine for the treatment of various symptoms associated with acute attacks of haemorrhoids, and also for the treatment of various symptoms associated with veno-lymphatic insufficiency (heaviness, pain in the legs, morning soreness and discomfort). The action characteristics of Diosmin are as follows:

1. It has specific affinity to the venous system and enhances the tension of the veins without affecting the arterial system; 2. It can reduce the viscosity of the blood in the microcirculatory system and increase the flow rate to reduce stagnation;

3、It can enhance the contraction of lymphatic vessels and the speed of lymphatic drainage in the lymphatic system, and accelerate the reflux to reduce oedema.

4、The commercially available Diosmin adopts micronisation technology, which increases the contact area after the use of the drug, more absorption and higher bioavailability.

It is suitable for all kinds of haemorrhoids and acute episodes of haemorrhoids, and can also treat chronic venous insufficiency, such as varicose veins, lower limb ulcers and so on.

Chemical Properties of Diosmin Raw Powder.

Diosmin is soluble in dimethyl sulfoxide and strong alkaline solutions, insoluble in water, methanol or ethanol, very slightly soluble in 0.1 mol/L sodium hydroxide.